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Wixela Inhub vs. Cinqair

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Wixela Inhub (fluticasone/salmeterol) and Cinqair (reslizumab) are both used to manage asthma, but they work in different ways and have some key differences. Wixela Inhub is an inhaled medication that combines a corticosteroid and a long-acting beta agonist to reduce inflammation and open airways. It's used for both asthma and COPD and is taken twice daily. In contrast, Cinqair is an intravenous infusion given by a healthcare provider once a month, specifically for severe asthma that isn't well-controlled by other medications. Cinqair is a monoclonal antibody that targets eosinophils, a type of white blood cell involved in inflammation. Wixela Inhub can be used in children as young as 4 years old, while Cinqair is only for adults. Additionally, Wixela Inhub has a generic version, whereas Cinqair does not. Both medications can cause serious allergic reactions, but Cinqair also carries a risk of cancerous tissue growth and parasitic infections.

Wixela Inhub

(fluticasone / salmeterol)

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Cinqair

(reslizumab)

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Summary for Wixela Inhub

Prescription only

Wixela Inhub is a combination inhaler that contains fluticasone (an inhaled corticosteroid) and salmeterol (a long-acting beta agonist, or LABA). This medication is used as maintenance treatment of chronic obstructive pulmonary disease (COPD) and asthma in adults and children. It's inhaled by mouth twice daily. Some of the more common side effects of Wixela Inhub (fluticasone / salmeterol) include upper respiratory tract infections, sore throat, and headaches. Wixela Inhub is the generic version of Advair Diskus.

Indications for Wixela Inhub

  • Maintenance treatment of asthma
  • Maintenance treatment of COPD - Wixela Inhub 250/50 only

Pros and Cons for Wixela Inhub

Pros

  • Works well to lower the risk of asthma or COPD symptoms
  • Combines two medications into a single inhaler for convenience
  • Can be used in children as young as 4 years old with asthma

Cons

  • Not a rescue inhaler for treating sudden trouble breathing
  • Needs to be used twice per day
  • Can cause fungal infections (thrush) in your mouth and throat
  • Not a good choice for people allergic to lactose

Common Side Effects for Wixela Inhub

  • Upper respiratory infection (up to 27%)
  • Sore throat (up to 13%)
  • Headache (up to 13%)
  • Bronchitis (up to 8%)
  • Cough (up to 6%)
  • Nausea and vomiting (up to 6%)
  • Hoarseness and changes in voice (up to 5%)
  • Sinus infection (up to 5%)

Warnings for Wixela Inhub

  • Not for use in asthma attack or for worsening breathing
  • Fungal infection in the mouth
  • Narrowing of your airways (bronchospasm)
  • Higher risk of infections
  • Altered stress hormone levels
  • Delayed growth in children
  • Eye and vision problems
  • Heart problems
  • Low potassium levels in the blood
  • Allergic reactions

Summary for Cinqair

Prescription only

Cinqair (reslizumab) is an intravenous (IV) infusion given by a healthcare provider to treat severe asthma in adults when other medications aren't working well enough. It's not meant for use during asthma attacks.

Indications for Cinqair

  • Severe asthma

Pros and Cons for Cinqair

Pros

  • Only has to be given once a month
  • Prevents worsening of asthma and can lower the number of asthma attacks
  • Good option when other asthma medications aren't working well enough
  • Not too many side effects

Cons

  • Has to be given in a healthcare facility; can't be injected at home
  • Only works for people with asthma caused by eosinophils
  • Can't be used in children
  • Can cause a severe allergic reaction

Common Side Effects for Cinqair

  • Mouth and throat pain (3%)
  • Muscle pain (2%)

Warnings for Cinqair

  • Life-threatening allergic reaction
  • Sudden breathing problems (asthma attacks)
  • Cancerous tissue growth
  • Using corticosteroids
  • Parasitic infections

Prices with our coupons for Wixela Inhub vs. Cinqair

Price Card Drug Icon
Wixela Inhub1 diskus inhaler / 250mcg/50mcg
$65.46$315.14
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Cinqair1 vial / 10ml of 100mg/10ml
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