Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Budesonide (Pulmicort Flexhaler) and albuterol (ProAir HFA, Ventolin HFA) are both inhaled medications used to manage asthma, but they belong to different medication classes and serve distinct purposes. Budesonide is an inhaled corticosteroid (ICS) used for the maintenance treatment of asthma in people aged 6 years and older. It works by reducing inflammation in the lungs and is typically taken twice daily. Albuterol, on the other hand, is a short-acting beta agonist (SABA) used as a rescue inhaler to quickly relieve sudden wheezing or shortness of breath in people aged 4 years and older. It is taken every 4 to 6 hours as needed. Budesonide is not used for immediate relief during an asthma attack, while albuterol provides quick relief within minutes. Budesonide is available in two strengths (90 mcg and 180 mcg per inhalation), whereas albuterol delivers 90 mcg per inhalation. Common side effects of budesonide include symptoms of the common cold and sore throat, while albuterol may cause sore throat and runny nose. Even though it's an inhaler, albuterol can interact with some oral medications, including beta blockers and digoxin.
Pulmicort flexhaler (budesonide)
Albuterol
Pulmicort flexhaler (budesonide)
Albuterol
Summary of Pulmicort Flexhaler vs. Albuterol
Summary for Inhaled corticosteroid (ICS)
Prescription only
Pulmicort Flexhaler (budesonide) is an inhaled corticosteroid. It's used in adults and children for the maintenance treatment of asthma. It's a type of dry powder inhaler that's inhaled through the mouth twice per day. Side effects include the common cold and sore throat.
Summary for SABA
Prescription only
Albuterol sulfate is a short-acting beta agonist (SABA). It's a rescue inhaler that treats or prevents sudden wheezing or shortness of breath in adults and children at least 4 years old with certain breathing problems, such as asthma. Albuterol is inhaled through the mouth using either an HFA inhaler (or metered dose inhaler) or a dry powder inhaler. The typical dose is 2 inhalations every 4 to 6 hours as needed when you suddenly have trouble breathing. Albuterol side effects generally include sore throat, throat irritation, and infections.
Indications of Pulmicort Flexhaler vs. Albuterol
Indications for
•Maintenance treatment of asthma in people ages 6 years and older
Indications for
•Treatment or prevention of wheezing or tightening of airways in people ages 4 years and older with certain types of lung problems (e.g., asthma)