Key takeaways
Zaleplon (Sonata) and flurazepam (formerly branded as Dalmane) are both medications used to treat insomnia, but they belong to different drug classes and have distinct characteristics. Zaleplon is a non-benzodiazepine sedative-hypnotic that helps you fall asleep quickly but doesn't help you stay asleep. In contrast, flurazepam is a benzodiazepine that helps you both fall asleep and stay asleep throughout the night. Zaleplon is typically used for short-term treatment (up to 30 days) and is available as a lower-cost generic, while flurazepam can be used for up to 28 days and is also available in generic form. Both medications can be habit-forming and may cause dependence, but flurazepam has a higher risk of side effects, especially for females and older adults. Additionally, both medications can cause unusual behaviors like sleepwalking and sleep-driving, but flurazepam has a broader range of common side effects, including headache and upset stomach.
