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Soliqua 100/33 vs. Toujeo

Soliqua 100/33 is a combination medication for diabetes that contains insulin glargine (a long-acting insulin) and lixisenatide (a glucagon-like peptide-1 (GLP-1) receptor agonist). It helps manage blood sugar levels along with diet and exercise in adults with Type 2 diabetes. The medication comes as a prefilled pen and is injected under the skin once a day within 1 hour before you eat your first meal of the day. Soliqua 100/33 commonly causes stomach-related side effects like nausea and diarrhea.

• Type 2 diabetes in adults

• Nausea (10%)
• Low blood sugar (8%)
• Common cold-like symptoms (7%)
• Diarrhea (7%)
• Headache (5%)

• Severe allergic reactions
• Inflammation of the pancreas (pancreatitis)
• Risk of high and low blood sugar levels
• Dangerously low blood sugar levels (hypoglycemia)
• Kidney damage
• Low blood potassium levels
• Fluid buildup and heart failure with certain diabetes medications
• Gallbladder problems
• Aspiration during anesthesia or sedation

Toujeo SoloStar and Toujeo Max SoloStar are a pair of brand names for insulin glargine. It's a long-acting insulin that's used for diabetes in adults and children. This medication is a more concentrated version of insulin glargine containing 300 units/mL. Toujeo (insulin glargine) comes as prefilled pens. You inject the medication under the skin once daily. Side effects include common cold symptoms and low blood sugar.

• Type 1 diabetes
• Type 2 diabetes

• Common cold symptoms
• Upper respiratory tract infection
• Low blood sugar

• Risk of infections with pen sharing
• Risk of changes to blood sugar levels with changes to your insulin regimen
• Low blood sugar (hypoglycemia)
• Low potassium levels
• Swelling and heart failure when used with certain diabetes medications
• Allergic reactions