Soliqua 100/33 vs. Tresiba for Diabetes Type 2: Important Differences and Potential Risks.

Soliqua 100/33

Insulin degludec

(Tresiba)

Summary for Soliqua 100/33

Prescription only

Soliqua 100/33 is an injectable medication for adults with Type 2 diabetes. It contains insulin glargine (a long-acting insulin) and lixisenatide (a glucagon-like peptide-1 (GLP-1) receptor agonist). It helps manage blood sugar levels along with a diabetes-friendly diet and exercise. Soliqua 100/33 comes as a prefilled pen. The medication is injected under the skin once a day within 1 hour before you eat your first meal of the day. Soliqua 100/33 can cause stomach-related side effects like nausea and diarrhea.

Indications for Soliqua 100/33

Type 2 diabetes in adults

Pros and Cons for Soliqua 100/33

Pros

Combines two diabetes medications into one injection
Injected under the skin once a day
Can help lower A1C by about 1% after several months

Cons

Must inject within 1 hour before your first meal of the day
Risk of low blood sugar, especially if meals are skipped or delayed
Can cause nausea and diarrhea

Common Side Effects for Soliqua 100/33

Nausea (10%)
Low blood sugar (8%)
Cold symptoms (7%)
Diarrhea (7%)
Headache (5%)
Upper respiratory tract infection (5%)

Warnings for Soliqua 100/33

Don't share Soliqua 100/33 pens
Severe allergic reactions
Inflammation of the pancreas (pancreatitis)
Risk of too high or too low blood sugar with changes to your insulin regimen
Low blood sugar levels (hypoglycemia)
Severe stomach side effects
Kidney damage due to dehydration
Low potassium levels
Fluid buildup and risk of heart failure when used with certain diabetes medications
Gallbladder problems
Lung problems during general anesthesia or deep sedation

Summary for Tresiba

Prescription only

Insulin degludec (Tresiba) is an ultra-long-acting insulin. It's used to manage blood sugar levels in adults and children with Type 1 diabetes or Type 2 diabetes. It's injected under the skin once per day. Insulin degludec (Tresiba) comes as a vial and FlexTouch pen. Side effects include common cold symptoms and headache. Tresiba is available as a brand-name medication and an unbranded biologic.

Indications for Tresiba

Pros and Cons for Tresiba

Pros

Injected once daily
Each dose can help control blood sugar levels for about 42 hours
Can be stored at room temperature for up to 2 months

Cons

Raises risk of dangerously low blood sugar levels
Might cause weight gain
Can't be mixed with other insulins

Common Side Effects for Tresiba

Low blood sugar levels (up to 99%)
Common cold (up to 24%)
Upper respiratory tract infection (up to 12%)
Headache (up to 12%)
Diarrhea (up to 6%)
Sinus infection (up to 5%)
Stomach viral infection (up to 5%)

Warnings for Tresiba

Risk of infections with pen sharing
Risk of high and low blood sugar levels
Dangerously low blood sugar levels (hypoglycemia)
Low blood potassium levels
Swelling and heart failure when used with certain diabetes medications
Allergic reactions

Prices with our coupons for Soliqua 100/33 vs. Tresiba

Soliqua 100/331 carton / 5 solostar pens of 3ml

$872.39$1,080.89

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Insulin Degludec1 vial / 10ml of 100 units/ml

$122.89$144.06

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Soliqua 100/33 vs. Tresiba

Soliqua 100/33

Insulin degludec

Summary for Soliqua 100/33

Indications for Soliqua 100/33

Pros and Cons for Soliqua 100/33

Pros

Cons

Common Side Effects for Soliqua 100/33

Warnings for Soliqua 100/33

Summary for Tresiba

Indications for Tresiba

Pros and Cons for Tresiba

Pros

Cons

Common Side Effects for Tresiba

Warnings for Tresiba

Prices with our coupons for Soliqua 100/33 vs. Tresiba

Compare other Diabetes Type 2 drugs

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Soliqua 100/33

Insulin degludec

Summary for Soliqua 100/33

Indications for Soliqua 100/33

Pros and Cons for Soliqua 100/33

Pros

Cons

Common Side Effects for Soliqua 100/33

Warnings for Soliqua 100/33

Summary for Tresiba

Indications for Tresiba

Pros and Cons for Tresiba

Pros

Cons

Common Side Effects for Tresiba

Warnings for Tresiba