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Compare Soliqua 100/33 vs. Tresiba

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Soliqua 100/33
    Insulin degludec (Tresiba)
  • Soliqua 100/33
    Insulin degludec (Tresiba)

  • Summary of Soliqua 100/33 vs. Tresiba

    Summary for Insulin / GLP-1 agonist
    Prescription only

    Soliqua 100/33 is a combination medication for diabetes that contains insulin glargine (a long-acting insulin) and lixisenatide (a glucagon-like peptide-1 (GLP-1) receptor agonist). It helps manage blood sugar levels along with diet and exercise in adults with Type 2 diabetes. The medication comes as a prefilled pen and is injected under the skin once a day within 1 hour before you eat your first meal of the day. Soliqua 100/33 commonly causes stomach-related side effects like nausea and diarrhea.

    Summary for Insulin
    Prescription only

    Insulin degludec (Tresiba) is an ultra-long-acting insulin. It's used to manage blood sugar levels in adults and children with Type 1 diabetes or Type 2 diabetes. It's injected under the skin once per day. Insulin degludec (Tresiba) comes as a vial and FlexTouch pen. Side effects include common cold symptoms and headache. Tresiba is available as a brand-name medication and an unbranded biologic.

  • Indications of Soliqua 100/33 vs. Tresiba

    Indications for
    •Type 2 diabetes in adults
    Indications for
    •Type 1 diabetes
    •Type 2 diabetes

  • Pros and Cons of Soliqua 100/33 vs. Tresiba

    Pros and Const for Insulin / GLP-1 agonist
    Pros
    •Lowers A1C by about 1%
    •Conveniently combines two medications in one injection
    •Injected under the skin once a day
    Cons
    •Risk of low blood sugar, especially if meals are skipped or delayed
    •Commonly causes stomach-related side effects like nausea and diarrhea
    •Must be taken within 1 hour before the first meal of the day
    Pros and Const for Insulin
    Pros
    •Injected once daily
    •Each dose can help control blood sugar levels for about 42 hours
    •Can be stored at room temperature for up to 2 months
    Cons
    •Raises risk of dangerously low blood sugar levels
    •Might cause weight gain
    •Can't be mixed with other insulins

  • Common Side Effects of Soliqua 100/33 vs. Tresiba

    Common Side Effects for
    •Nausea (10%)
    •Low blood sugar (8%)
    •Common cold-like symptoms (7%)
    •Diarrhea (7%)
    •Headache (5%)
    Common Side Effects for
    •Low blood sugar levels (up to 99%)
    •Common cold (up to 24%)
    •Upper respiratory tract infection (up to 12%)
    •Headache (up to 12%)
    •Diarrhea (up to 6%)
    •Sinus infection (up to 5%)
    •Stomach viral infection (up to 5%)

  • Warnings of Soliqua 100/33 vs. Tresiba

    Common Side Effects for
    •Severe allergic reactions
    •Inflammation of the pancreas (pancreatitis)
    •Risk of high and low blood sugar levels
    •Dangerously low blood sugar levels (hypoglycemia)
    •Kidney damage
    •Low blood potassium levels
    •Fluid buildup and heart failure with certain diabetes medications
    •Gallbladder problems
    •Aspiration during anesthesia or sedation
    Common Side Effects for
    •Risk of infections with pen sharing
    •Risk of high and low blood sugar levels
    •Dangerously low blood sugar levels (hypoglycemia)
    •Low blood potassium levels
    •Swelling and heart failure when used with certain diabetes medications
    •Allergic reactions

  • Prices with our coupons for Soliqua 100/33 vs. Tresiba

    Learn more about Soliqua 100/33
    Learn more about Insulin degludec

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