Key takeaways
Glycopyrrolate (Robinul) and Oxybutynin ER (Ditropan XL) are both anticholinergic medications, but they are used for different conditions. Glycopyrrolate is primarily used as an add-on treatment for stomach ulcers, while Oxybutynin ER is used to treat overactive bladder (OAB). Glycopyrrolate is available in both oral tablet and orally disintegrating tablet forms, whereas Oxybutynin ER comes in extended-release tablets, as well as short-acting tablets, oral syrup, and oral solution. Glycopyrrolate is taken two to three times daily, while Oxybutynin ER is typically taken once daily. Both medications can cause dry mouth, constipation, and dizziness, blurred vision, and sleepiness. Oxybutynin ER is not recommended for people with untreated narrow-angle glaucoma, difficulty urinating, or certain stomach and intestine problems, while Glycopyrrolate is not recommended for those with glaucoma, blocked urine flow, or stomach blockage.
