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Compare Maprotiline vs. Surmontil

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Maprotiline and trimipramine are both medications used to treat depression, but they belong to different classes. Maprotiline was a tetracyclic antidepressant, but is no longer available in the U.S. Trimipramine is a tricyclic antidepressant. Trimipramine is still available as a generic and can be taken in divided doses throughout the day or as a single dose at bedtime. Trimipramine can cause side effects like dizziness, dry mouth, and heart problems, and it may take several weeks to notice mood improvements. It also has potential interactions with other medications, especially those affecting serotonin levels.

  • Maprotiline
    Trimipramine
  • Maprotiline
    Trimipramine

  • Summary of Maprotiline vs. Surmontil

    Summary for Tetracyclic antidepressant
    Prescription only

    Maprotiline is an antidepressant used to treat depression and anxiety associated with depression. It's no longer available in the United States because it was discontinued.

    Summary for Tricyclic antidepressant
    Prescription only

    Trimipramine is taken by mouth and used to treat depression. It's not a first-choice medication because it can cause many side effects, such as dizziness, dry mouth, anxiety, or heart problems.

  • Indications of Maprotiline vs. Surmontil

    Indications for
    •Depression
    •Anxiety from depression
    Indications for
    •Depression

  • Pros and Cons of Maprotiline vs. Surmontil

    Pros and Const for Tetracyclic antidepressant
    Pros
    Cons
    Pros and Const for Tricyclic antidepressant
    Pros
    •Available as a lower-cost generic
    •Available in 3 different strengths, convenient if you need to adjust your dose
    •Can be taken once a day, usually before you go to bed
    Cons
    •Might not notice changes in your mood until you've taken trimipramine for several weeks
    •Stopping trimipramine suddenly can cause withdrawal symptoms, such as nausea, headache, and discomfort
    •Can cause more side effects than other medications used to treat depression
    •Not recommended for use for people with certain medical conditions, such as heart problems, thyroid problems, or seizures

  • Common Side Effects of Maprotiline vs. Surmontil

    Common Side Effects for
    Common Side Effects for
    •Drowsiness
    •Blood pressure changes
    •Feeling of pins and needles in your arms and legs
    •Dry mouth
    •Blurred vision
    •Nausea and vomiting

  • Warnings of Maprotiline vs. Surmontil

    Common Side Effects for
    Common Side Effects for
    •Suicidal thoughts or behavior
    •Possible bipolar disorder
    •Serotonin syndrome
    •Heart problems
    •Drowsiness or sleepiness
    •Withdrawal symptoms

  • Prices with our coupons for Maprotiline vs. Surmontil

    Learn more about Maprotiline
    Learn more about Trimipramine

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