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Maprotiline vs. Tofranil

Maprotiline is an antidepressant used to treat depression and anxiety associated with depression. It's no longer available in the United States because it was discontinued.

• Depression
• Anxiety from depression

Imipramine is a medication that's used to treat depression. It can also temporarily help with bedwetting in children at night. Imipramine belongs to a class of medications called tricyclic antidepressants (TCAs). There are two different forms of the medication: imipramine hydrochloride and imipramine pamoate. They used to be available under the brand name Tofranil but are now only sold as generic versions. The dosage generally depends on why you need imipramine, how severe your symptoms are, and your age. It's generally not a first-choice option because it can cause a lot of side effects, like sleepiness, dizziness, dry mouth, and changes in weight.

• Depression
• Bedwetting in children (imipramine hydrochloride only)

In adults (with depression)

• Dry mouth
• Blurry vision
• Nausea
• Vomiting
• Constipation
• Sleepiness
• Dizziness
• Confusion
• Anxiety
• Restlessness

In children (with bedwetting problems)

• Nervousness
• Sleep problems
• Tiredness
• Stomach upset

• Worsening depression, suicidal thoughts, and unusual behavior
• Not for use alone in bipolar disorder
• Risk of heart problems, heart attack, or stroke
• Glaucoma
• Higher risk of falls
• Seizures