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Jeuveau vs. Botox

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Jeuveau (prabotulinumtoxinA-xvfs) and Botox (onabotulinumtoxinA) are both neuromuscular blockers used to treat wrinkles, specifically frown lines. However, they have different FDA-approved uses. Jeuveau is only approved for cosmetic use to improve moderate-to-severe frown lines in adults, while Botox has a broader range of uses, including treating overactive bladder, chronic migraines, muscle spasms, and excessive sweating. Both medications are given as injections by a healthcare provider, but Botox is available in more dosage forms for different conditions. Jeuveau is typically injected into the forehead, while Botox can be used in various body areas depending on the condition being treated. Common side effects of both medications include headaches and injection site reactions. Both medications carry risks of serious side effects if the toxin spreads/ Botox has additional side effects and warnings related to bladder and eye conditions since it can be administered for other conditions. Neither medication is available in generic form, which may affect cost considerations.

Jeuveau

(prabotulinumtoxinA)

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Botox

(onabotulinumtoxinA)

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Summary for Jeuveau

Prescription only

Jeuveau (prabotulinumtoxinA or prabotulinumtoxinA-xvfs) is a neuromuscular blocker made of botulism toxin. It's injected into certain muscles on the forehead to improve the looks of frown lines in adults. If you need more than one treatment, your HCP can inject Jeuveau (prabotulinumtoxinA) at most once every 3 months. Jeuveau (prabotulinumtoxinA) should only be given by a licensed healthcare professional (HCP) in a healthcare setting. Some common side effects of this medication include headache and pain at the injection site.

Indications for Jeuveau

  • Temporary improvement in moderate-to-severe frown lines (glabellar lines) in adults

Pros and Cons for Jeuveau

Pros

  • Works well to improve the appearance of moderate-to-severe frown lines
  • Injected directly at the affected area on the forehead
  • Effects can last many months after each treatment

Cons

  • Results aren't permanent, might need re-treatment
  • Can experience headaches as side effects
  • Unknown if safe to use during pregnancy or breastfeeding

Common Side Effects for Jeuveau

  • Headache (12%)
  • Upper respiratory tract infection (e.g., common cold; 3%)
  • Drooping eyelid (2%)

Warnings for Jeuveau

  • Spread of toxin effects
  • Severe allergic reactions
  • Difficulty swallowing or breathing
  • Worsening of certain conditions
  • Dry eyes

Summary for Botox

Prescription only

Botox (onabotulinumtoxinA) is a prescription injection used for many medical conditions caused by muscle overactivity or nerve problems. It's FDA approved for treating conditions like overactive bladder, excessive armpit sweating, and for preventing migraines. The medication is injected by a trained healthcare professional. Side effects depend on where the injection is given, but they can include urinary tract infections, headache, and neck pain.

Botox (onabotulinumtoxinA) is different from Botox Cosmetic, which is used for facial and neck lines.

Indications for Botox

Pros and Cons for Botox

Pros

  • FDA approved to treat many different conditions
  • Might be a good option when other treatments have failed
  • Injected directly into the area causing trouble
  • Effects last a few months

Cons

  • Needs to be injected by a healthcare professional
  • Injections can be uncomfortable
  • Has serious risks if the toxin spreads to other parts of your body
  • Might need to get repeat treatments

Common Side Effects for Botox

Overactive bladder:

  • Urinary tract infection (18%)
  • Painful urination (9%)
  • Trouble emptying the bladder (6%)

Loss of bladder control:

  • Urinary tract infection (24-26%)
  • Urine left in the bladder (17%)
  • Trouble emptying the bladder (15-17%)
  • Difficulty passing urine (15%)

Chronic migraine:

  • Neck pain (9%)
  • Headache (5%)

Muscle spasms:

  • Pain in the arm or leg (up to 9%)
  • Muscle weakness (up to 4%)

Neck muscle spasm:

  • Trouble swallowing (19%)
  • Upper respiratory infection (12%)
  • Neck pain (11%)
  • Headache (11%)

Excessive armpit sweating:

  • Injection site pain (3-10%)
  • Bleeding (3-10%)
  • Infection (3-10%)

Eyelid twitching:

  • Droopy eyelid (21%)
  • Damage to surface of the eye (6%)
  • Dry eye (6%)

Crossed eyes:

  • Droopy eyelid (1-38%)
  • Eye misalignment (17%)

Warnings for Botox

  • Spread of toxin effect
  • Serious allergic reaction
  • Difficulty swallowing or breathing
  • Lung problems in people with breathing conditions
  • Eye problems and bleeding
  • Bronchitis and upper respiratory tract infections
  • Overactive nervous system
  • Urinary tract infections
  • Trouble emptying the bladder
  • Transmission of diseases

Prices with our coupons for Jeuveau vs. Botox

Price Card Drug Icon
Jeuveau1 vial / 100 units
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Botox1 vial / 100 units
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