Key takeaways
Janumet (sitagliptin / metformin) and metformin are both medications used to treat Type 2 diabetes. They help control blood sugar levels and are taken orally. While they have similar active ingredients, there are some differences between the two medications. Janumet is a combination of a dipeptidyl peptidase-4 (DPP-4) inhibitor (sitagliptin) and a biguanide (metformin), while metformin alone does not contain any other active ingredients. Janumet is taken twice a day with meals, whereas metformin is typically taken two to three times a day, also with meals. Janumet is only available as a brand-name medication, while metformin is available in generic form and as a liquid for those who have trouble swallowing tablets. Common side effects of Janumet include diarrhea, upper respiratory tract infection, and headache, while metformin commonly causes diarrhea, nausea, and gas. Both medications can interact with alcohol and certain diabetes medications, increasing the risk of lactic acidosis and low blood sugar, respectively.
