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Aubagio vs. Tecfidera

Teriflunomide (Aubagio) helps treat relapsing forms of multiple sclerosis (MS) in adults. It's a type of disease-modifying therapy (DMT) that helps slow down MS and lower the number of relapses. The typical dose is 1 tablet by mouth once a day. Side effects includes headache, diarrhea, and hair loss. Teriflunomide (Aubagio) comes as a brand-name and generic medication.

• Relapsing forms of multiple sclerosis (MS)

• Headache (up to 18%)
• Higher liver enzyme levels (up to 15%)
• Diarrhea (up to 14%)
• Hair loss (up to 13%)
• Nausea (up to 11%)

• Liver problems
• Harm to an unborn baby
• Special instructions to remove teriflunomide (Aubagio) from the body quickly
• Risk of serious infections
• Serious skin reactions
• Severe allergic reactions
• Nerve problems
• Lung problems

Dimethyl fumarate (Tecfidera) is used to treat adults with certain types of multiple sclerosis (MS), a condition that affects your nervous system. This medication is a disease-modifying therapy (DMT) that belongs to the drug class called fumaric acid derivatives. Dimethyl fumarate (Tecfidera) is available as a brand-name medication and a lower-cost generic. The capsules are taken by mouth twice per day. The most common side effects are stomach upset and flushing (e.g., facial warmth, redness, burning sensation).

• Relapsing forms of multiple sclerosis (MS)

• Flushing (40%)
• Stomach pain (18%)
• Diarrhea (14%)
• Nausea (12%)
• Vomiting (9%)
• Itchiness (8%)
• Rash (8%)

• Severe allergic reactions
• Serious infections
• Low white blood cell counts (lymphopenia)
• Liver damage
• Flushing
• Serious stomach and intestine problems