Insulin / GLP-1 agonist combinations are used to treat Type 2 diabetes. They work by combining insulin, which helps your body use glucose (sugar) for energy, with a GLP-1 agonist, which increases natural insulin release and decreases glucose production in the liver. These combinations are typically injectable. Examples include insulin glargine / lixisenatide (Soliqua 100/33) and insulin degludec / liraglutide (Xultophy). You can discuss with your healthcare team which option might be right for you.