Benazepril (Lotensin) is a first-choice medication used to lower blood pressure. It's taken by mouth, typically once or twice daily. Some of the more common side effects of benazepril (Lotensin) include headache and dizziness. You shouldn't take this medication if you're pregnant because it can cause serious complications and birth defects. Benazepril (Lotensin) is available as a lower cost generic.
High blood pressure
Benazepril (Lotensin) is an angiotensin-converting enzyme (ACE) inhibitor. It blocks the production of a chemical that tightens blood vessels. Without this chemical, you blood vessels relax and your body holds on to less fluid. This causes your blood pressure to go down.
Source: DailyMed
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
Chills
cold sweats
confusion
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
unusual tiredness or weakness
Incidence not known
Arm, back, or jaw pain
blistering, peeling, or loosening of the skin
bloating or swelling of the face, arms, hands, lower legs, or feet
chest pain or discomfort
fast, irregular, pounding, or racing heartbeat or pulse
feeling of warmth
general feeling of tiredness or weakness
joint or muscle pain
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
rapid breathing
rapid weight gain
red skin lesions, often with a purple center
red, irritated eyes
redness of the face, neck, arms, and occasionally, upper chest
skin rash
sores, ulcers, or white spots in the mouth or on the lips
sweating
tingling of the hands or feet
unusual weight gain or loss
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Headache
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
A first-choice blood pressure medication for many people
Can protect kidney function in people with diabetes or mild-to-moderate kidney disease
Lowers the risk of heart attack and stroke in people with high blood pressure
Available as a lower-cost generic
Can cause dry cough
Can't take if you're pregnant
Might not work as well in Black people
Can cause dizziness and raise the risk for falls
You can take benazepril (Lotensin) with or without food. Food won't affect how well this medication works for you.
If you're checking your blood pressure at home, record your measurements and let your provider know if it hasn't improved after a week or so.
Benazepril (Lotensin) can cause dizziness. You're more likely to experience dizziness when you first start taking benazepril (Lotensin), or when your provider raise your dose. The should get better over time as you continue taking the medication and your body gets used to your new blood pressure. But let your provider know if you continue to experience dizziness because they might need to lower your dose of benazepril (Lotensin) or switch you to a different medication.
Some people get a dry cough while taking benazepril (Lotensin). This can happen at any time, even if you've been taking the medication for years. You can still have a cough for many weeks after stopping benazepril (Lotensin). Let your provider know if the cough bothers you because they can help choose a different blood pressure medication for you.
If you miss a dose, take it as soon as you remember. But if it's almost time for your next dose, skip the missed dose. Don't "double up" to make up for the missed dose as this can drop your blood pressure too much.
Though rare, benazepril (Lotensin) can cause liver or kidney problems in some people. It can also raise potassium levels, which can be dangerous. Your provider might order blood tests to check your kidney or liver health, or potassium levels.
Let your provider know if you're pregnant or plan on becoming pregnant. This medication can cause birth defects. Your provider can talk with you about safer options to control your blood pressure during pregnancy.
Benazepril (Lotensin) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Benazepril (Lotensin) can cause birth defects (e.g., issues with skeleton development, lung development, problems with the unborn baby's kidneys, or even death). The risk is higher if you take this medication during the second or third trimester of pregnancy. If you're pregnant, let your provider know right away and stop taking benazepril (Lotensin) as soon as possible.
Risk factors: Taking mTOR inhibitors with benazepril (Lotensin) | Black people
Angioedema (swelling of the face, lips, tongue, throat, or other organs) can happen at any time while you're taking benazepril (Lotensin). Sometimes, angioedema can affect your stomach and you might experience symptoms such as nausea of vomiting. You're more likely to experience angioedema if you're Black, an older adult, or female. Get medical help right away if you have trouble breathing, swelling of the tongue, nausea, or vomiting.
Risk factors: History of kidney problems | Severe congestive heart failure
Benazepril (Lotensin) is usually good for the kidneys. But in some cases it can make kidney problems worse. The risk is higher for people who have certain types of kidney problems, such as renal artery stenosis or very severe heart failure. Your provider might order lab tests every so often to make sure your kidneys are healthy and working properly. Your provider will check your kidneys before starting benazepril (Lotensin) and regularly as needed. Let your provider know if you're urinating less often than usual, as this could be a sign that your kidneys aren't working as well.
Risk factors: Diabetes | Kidney problems | Taking other medications that also raise potassium
Benazepril (Lotensin) can raise the amount of potassium in your body, which can be dangerous. Your risk of developing high potassium is greater if you have diabetes, kidney problems, or are taking other medications that also raise potassium levels. For this reason, make sure your provider knows your full medical history and what medications you're taking before starting benazepril (Lotensin). If you experience signs of high potassium levels, such as nausea, muscle weakness, or abnormal heartbeat, tell your healthcare provider right away.
Risk factors: Heart failure | Dialysis | Low fluids in the body | Taking other medicines that lower your blood pressure
Benazepril (Lotensin) lowers your blood pressure and can make you feel lightheaded or dizzy. Your risk of developing dangerously low blood pressure is greater if you have heart problems or if you're dehydrated (not enough fluid in your body). If you start to feel lightheaded or dizzy on this medication, especially right after a dose change, make sure to hold onto something when you're getting up from a sitting or lying down position. Also, call your provider right away.
In some rare cases, people who took ACE inhibitors like benazepril (Lotensin) have developed a blocked bile duct. This condition can lead to liver problems or liver failure. Your provider might order blood tests to check your liver health from time to time. If you notice symptoms of liver problems, such as tiredness, stomach pain, or yellowing of your skin, let your provider know right away.
Adults
The typical starting dose of benazepril (Lotensin) is 10 mg by mouth once daily. The recommended maintenance dose ranges from 20 mg to 40 mg taken once daily, or split into two doses and taken twice daily. If you're also taking a water pill, the typical starting dose of benazepril (Lotensin) is 5 mg by mouth once daily.
Children (age 6 years and older)
Your child's provider will calculate your child's dose based on their weight. The typical starting dose is 0.2 mg/kg taken by mouth once daily. If needed, your child's provider will raise their dose slowly over time. The maximum dose is 0.6 mg/kg once daily.
Your dose might differ if you've kidney problems.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
History of angioedema
Taking benazepril (Lotensin) with a neprilysin inhibitor (e.g., sacubitril)
Have diabetes and are taking aliskiren (Tekturna)
High blood pressure
Heart failure
Lower the risk for death after a heart attack
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Dahal, S. S., et al. (2023). Benazepril. StatPearls.
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. (2023). BENAZEPRIL HYDROCHLORIDE tablet [package insert]. DailyMed.
MedlinePlus. (2017). Benazepril.
Montford, J.R., et al. (2017). How dangerous is hyperkalemia? Journal of the American Society of Nephrology : JASN.
Schoolwerth, A. C., et al. (2001). Renal considerations in angiotensin converting enzyme inhibitor therapy: A statement for healthcare professionals from the Council on the Kidney in Cardiovascular Disease and the Council for High Blood Pressure Research of the American Heart Association. Circulation.
Whelton, P. K., et al. (2017). 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension.
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