provider image
Welcome! You’re in GoodRx for healthcare professionals. Now, you’ll enjoy a streamlined experience created specifically for healthcare professionals.
Skip to main content
Simvastatin Coupon - Simvastatin 20mg tablet

simvastatin

Generic Zocor
Used for Coronary Artery Disease, High Cholesterol
Used for Coronary Artery Disease, High Cholesterol

Simvastatin (Zocor) is a statin used to lower your cholesterol to help protect your heart and blood vessels from serious, and even life-threatening, medical problems, such as heart attack or stroke. Simvastatin (Zocor) isn't meant to lower cholesterol on its own. Instead, you should take it in addition to eating a healthy diet and having a regular exercise routine. To get the most out of the medication, it's best to take simvastatin (Zocor) nightly before going to sleep.

Last reviewed on December 7, 2022
basics-icon

What is Simvastatin (Zocor)?

What is Simvastatin (Zocor) used for?

How Simvastatin (Zocor) works

Simvastatin (Zocor) is a statin. The main way it works is by blocking an enzyme (protein) in your liver that makes cholesterol. As a result, simvastatin (Zocor) lowers your "bad" cholesterol (called low-density lipoprotein, or LDL). Simvastatin (Zocor) can also raise your "good" cholesterol (called high-density lipoprotein, or HDL) levels and lower your triglyceride levels.

Are you looking for information on Vytorin (ezetimibe / simvastatin) instead?

Drug Facts

Common BrandsZocor, Flolipid
Drug ClassStatin
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only

More on Simvastatin (Zocor) essentials

coupon-save-icon

Get your GoodRx coupon

Avg retail price
$66.12(save 83.89%)
GoodRx discount
$10.65
See prices
basics-icon

What are the side effects of Simvastatin (Zocor)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Cough, runny nose, and other symptoms of bronchitis (7%)
  • Stomach pain (6%)
  • Irregular heart beat (6%)
  • Nausea, stomach pain ,and other symptoms of stomach inflammation (5%)
  • Eczema (dry, itchy skin) (5%)
  • Dizziness (5%)

Other Side Effects

  • Diabetes
  • Difficulty sleeping
  • Muscle pain
  • Urinary tract infection
  • Swelling in hands, legs, or feet
  • Headache
  • Sinus infection
  • Constipation

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Severe muscle damage (rhabdomyolysis): Dark brown urine, severe muscle weakness or pain, fever, tiredness
  • Worsening liver problems or liver failure: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion, dark or brown urine

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Dizziness

fainting

fast or irregular heartbeat

Less common

Bladder pain

bloody or cloudy urine

blurred vision

body aches or pain

chills

cough

dark-colored urine

difficult, burning, or painful urination

difficulty with breathing

difficulty with moving

dry mouth

ear congestion

fever

flushed, dry skin

frequent urge to urinate

fruit-like breath odor

headache

increased hunger

increased thirst

increased urination

joint pain

loss of consciousness

lower back or side pain

muscle cramps, spasms, stiffness, pain, tenderness, wasting, or weakness

nausea

runny or stuffy nose

sneezing

sore throat

stomachache

sweating

swelling

swollen joints

trouble breathing

unexplained weight loss

unusual tiredness or weakness

vomiting

Incidence not known

Blistering, peeling, or loosening of the skin

bloating

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

constipation

diarrhea

difficulty with swallowing

general tiredness and weakness

indigestion

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

light-colored stools

loss of appetite

pains in the stomach, side, or abdomen, possibly radiating to the back

pale skin

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

red skin lesions, often with a purple center

red, irritated eyes

skin rash, hives, or itching

sores, ulcers, or white spots in the mouth or on the lips

tightness in the chest

unusual bleeding or bruising

upper right abdominal or stomach pain

weakness in the arms, hands, legs, or feet

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Acid or sour stomach

belching

burning feeling in the chest or stomach

dizziness or lightheadedness

excess air or gas in the stomach or intestines

feeling of constant movement of self or surroundings

full feeling

heartburn

lack or loss of strength

pain or tenderness around the eyes and cheekbones

passing gas

sensation of spinning

skin rash, encrusted, scaly, and oozing

stomach discomfort, upset, or pain

tenderness in the stomach area

trouble sleeping

Incidence not known

Being forgetful

depression

discoloration of the skin

hair loss or thinning of the hair

inability to have or keep an erection

loss in sexual ability, desire, drive, or performance

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Simvastatin (Zocor)

thumbs-up

Pros

Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL)

Can help lower the risk of heart attack and stroke

Oral solution (Flolipid) available for people who have trouble swallowing tablets

Can be used in children as young as 10 years old

thumbs-down

Cons

Can't take if you've certain liver problems

Risk of side effects are higher in certain people, such as those age 65 years and older or those who drink alcohol daily

Simvastatin (Zocor) has the highest risk among the statins to cause rhabdomyolysis, a life-threatening muscle problem

pharmacist-tips

Pharmacist tips for Simvastatin (Zocor)

pharmacist
  • You can take simvastatin (Zocor) with or without food. But make sure to take the tablets whole.

    • Take your dose at night before going to sleep. This will help you get the most benefit from the medication. If it's challenging for you to take this medication at bedtime, ask your provider about taking it at a time that works best for you.

      • Limit the amount of alcohol you drink while taking simvastatin (Zocor). This is because alcohol can raise your risk of serious liver problems with simvastatin (Zocor). Ask your provider what's a safe amount of alcohol to drink while you're taking this medication.

        • Let your provider know right away if you experience muscle pain or weakness, especially if you also have fever or feel extremely tired. This can be a sign of a rare, but serious, breakdown of muscles called rhabdomyolysis.

          • Simvastatin (Zocor) interacts with many commonly prescribed medications. For example, amiodarone (Pacerone), amlodipine (Norvasc), and colchicine (Colcrys) can raise the level of simvastatin (Zocor) in your body and put you at higher risk for side effects, such as muscle damage. Make sure to let your provider know about all the medications you're taking (including vitamins and supplements) before starting simvastatin (Zocor).

            • Avoid grapefruit or grapefruit juice while taking simvastatin (Zocor) because it can raise the amount of the medication in your body, which raises your risk of side effects.

              • It's important that you eat a healthy and balanced diet low in fat and a maintain a regular exercise routine while taking simvastatin (Zocor). Doing so will help you get the most benefit out of the medication. Talk with your provider if you have questions about how to plan your meals and what kind of exercise is appropriate for you.

                • Make sure to mark your calendar with your appointments to see your provider and to get any blood work done when you take simvastatin (Zocor). Your provider will order blood work to check your cholesterol levels during treatment. They might change your dose of simvastatin (Zocor) based on your lab results.

                  Tips for Flolipid oral solution

                  • If you're taking Flolipid (simvastatin) oral solution, you need to take it on an empty stomach.

                    • Make sure to shake the bottle of Flolipid (simvastatin) for at least 20 seconds before using it. You need to measure your dose with a medication measuring device. Don't use household spoons to measure your dose because it might not be accurate.

                      • Please properly dispose your bottle of Flolipid (simvastatin) 30 days after you open it, even if there's still medication left. The remaining medication might not work well if you continue to use it after 30 days.

                        More on Simvastatin (Zocor) tips

                        faqs

                        Frequently asked questions about Simvastatin (Zocor)

                        Is simvastatin (Zocor) a first-choice medication to lower cholesterol?
                        Statins, like simvastatin (Zocor), are first-choice medications to lower cholesterol. But among the statins, it's hard to say whether or not one is better than another. Some statins are more potent, meaning they can lower your cholesterol levels more than other statins (if you compare them milligram to milligram). For example, simvastatin (Zocor) is considered a low-to-moderate intensity statin. At certain doses, simvastatin (Zocor) can lower your cholesterol levels by almost 50%. Your provider will determine if simvastatin (Zocor) is a good choice for you depending on factors, such as what other medications you might be taking and how high your LDL cholesterol level is.
                        Why do I need to take simvastatin (Zocor) at night?
                        Simvastatin (Zocor) is a short-acting statin, meaning its effects on cholesterol might wear off before the next dose. Since your body makes more cholesterol at night, then it might be better to take simvastatin (Zocor) in the evening. However, more research is needed to confirm this. If taking simvastatin (Zocor) at night is challenging for you, ask your provider if it's okay to take it at another time that works for you. The more important thing to keep in mind that it's better to take your simvastatin (Zocor) than to not take it at all.
                        What can I do if I get muscle pain from simvastatin (Zocor)?
                        Muscle pain is a well-known potential side effect of statins. You can experience it at any time during treatment, even if you've been taking simvastatin (Zocor) for years without any problem. Let your provider know right away if you experience muscle pain. They can recommend possible solutions, such as lowering your dose or change how often you take simvastatin (Zocor) (e.g., every other day instead of daily). Or, your provider might switch you to another statin because you might not get muscle pain from another statin just because you got muscle from simvastatin (Zocor). Be sure to get medical help right away if you also notice dark-colored urine or fever in addition to muscle pain - these might be signs of a very serious condition called rhabdomyolysis (muscle breakdown).
                        Is 80 mg of simvastatin (Zocor) a safe dose?
                        According to the manufacturer, the maximum recommended dose of simvastatin (Zocor) is 40 mg daily. In the past, it was 80 mg daily. In 2011, the FDA announced that 80 mg of simvastatin (Zocor) is no longer recommended after a large study showed the risk of severe muscle damage was 10-times higher in people taking 80 mg of simvastatin (Zocor) compared to those taking 20 mg or 40 mg of simvastatin (Zocor). Currently, the FDA recommends that health care providers can continue people on 80 mg of simvastatin (Zocor) if they had been on this dose for at least 1 year and if they didn't have any muscle injury. If you're currently taking simvastatin (Zocor) 80 mg daily and have concerns about muscle pain, talk with your provider.
                        Can I take simvastatin (Zocor) if I'm pregnant or breastfeeding?
                        No, you shouldn't take simvastatin (Zocor) if you're pregnant or breastfeeding. Although the FDA requested the warning against the use of statins during pregnancy be removed, they still encourage pregnant females stop using statins because it's not clear whether or not it's safe. However, based on how it works, it's possible for simvastatin (Zocor) to cause birth defects. In addition, simvastatin (Zocor) hasn't been studied in breastfeeding. But, based on similar medications, it can pass through breast milk and cause harm to breastfed babies. Ask your provider if you have any questions about simvastatin (Zocor) and pregnancy or breastfeeding.
                        GoodRxEducationalIcon

                        How to save using GoodRx

                        Compare Prices
                        1. Compare PricesSpecify your dosage and quantity to find out exactly how much you can save.
                        Select your free coupon
                        2. Select your free couponYou can use the displayed coupon, or compare prices at other pharmacies near you.
                        Show coupon to your pharmacist
                        3. Show coupon to your pharmacistPresent your printed or electronic coupon when you pick up your prescription.
                        Get free couponLearn more
                        warings-icon

                        What are the risks and warnings for Simvastatin (Zocor)?

                        Simvastatin (Zocor) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                        risk-warning

                        Severe muscle pain and damage

                        • Risk factors: Age 65 years and older | Higher dose of simvastatin (Zocor) | Kidney problems | Taking other medications that can also cause muscle problems or interact with simvastatin (Zocor) | Uncontrolled hypothyroidism

                          Simvastatin (Zocor) can cause a rare, but serious and life-threatening muscle problem called rhabdomyolysis. Your risk if higher if you take other medications that can raise the levels of simvastatin (Zocor) in your body. For this reason, don't start any new medications without asking your provider or pharmacist first. If you notice any of symptoms of rhabdomyolysis, such as severe muscle pain, dark-colored urine, weakness, and tiredness, stop simvastatin (Zocor) and get medical attention right away.

                          Rarely, statins can cause immune-mediated necrotizing myopathy (IMNM). In these cases, the pain might continue even if you stop taking the statin. If you develop IMNM, your provider will ask you to stop the statin and might treat you with medications to dampen down your immune system.

                          risk-warning

                          Worsening liver problems and liver failure

                          • Risk factors: History of liver problems | Drinking large amounts of alcohol

                            Though rare, simvastatin (Zocor) can cause serious liver problems that can lead to liver failure. You might need to get blood tests to check your liver health before and during treatment to make sure your liver is working properly. Get medical attention right away if you notice swelling of your stomach, stomach pain, yellowing of your skin or the whites of your eyes, stool changes (black, tarry, or bloody stools), nausea, vomiting, confusion, or dark or brown urine. You might need to stop using the medication to prevent further liver damage.

                            risk-warning

                            High blood sugar

                            • Risk factors: High blood sugar

                              Some research suggest that simvastatin (Zocor) can raise your blood sugars levels, which can lead to higher hemoglobin A1C levels. However, healthcare providers believe that the benefits of statins outweigh their risk for harm. Let your provider know if you have high blood sugar before starting simvastatin (Zocor) because you might need to monitor your blood sugar more often. Also, make sure to have a healthy, balanced diet and regular exercise while taking simvastatin (Zocor).

                              risk-warning

                              Possible harm during in pregnancy or breastfeeding

                              Simvastatin (Zocor) isn't recommended for use during pregnancy or breastfeeding for most people. This medication can cause harm to unborn and breastfed babies. If you're pregnant, thinking of becoming pregnant, or breastfeeding, ask your provider about the safest options for you.

                              More on Simvastatin (Zocor) warnings

                              dosage

                              Simvastatin (Zocor) dosage forms

                              The average cost for 90 tablets of 20mg of Simvastatin (Zocor) is $10.77 with a free GoodRx coupon. This is 83.71% off the average retail price of $66.12.
                              tablet
                              Tablet
                              DosageQuantityPrice as low asPrice per unit
                              5mg90 tablets$13.48$0.15
                              10mg90 tablets$11.06$0.12
                              20mg90 tablets$10.77$0.12
                              40mg90 tablets$10.65$0.12
                              80mg90 tablets$17.10$0.19

                              Typical dosing for Simvastatin (Zocor)

                              Simvastatin (Zocor) tablets

                              • Adults: The typical dose ranges from 20 mg to 40 mg by mouth once daily in the evening.

                              • Children age 10 years and older: The typical dose ranges from 10 mg to 40 mg by mouth once daily in the evening.

                              Flolipid (simvastatin) oral solution

                              • The typical dosing range is 5 mg to 40 mg by mouth once daily in the evening.

                              Your dose of simvastatin (Zocor) might be different if you have kidney problems or if you're taking certain medications.

                              More on Simvastatin (Zocor) dosage forms

                              interactions

                              Interactions between Simvastatin (Zocor) and other drugs

                              Simvastatin (Zocor) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Simvastatin (Zocor). Please note that only the generic name of each medication is listed below.

                              Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                              Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                              Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                              drug-cost

                              How much does Simvastatin (Zocor) cost?

                              To access savings, use a GoodRx coupon and pay just a fraction of the retail price.View prices & coupons
                              contraindications-icon

                              Simvastatin (Zocor) contraindications

                              Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Simvastatin (Zocor) will not be safe for you to take.
                              alternatives

                              What are alternatives to Simvastatin (Zocor)?

                              There are a number of medications that your doctor can prescribe in place of Simvastatin (Zocor). Compare a few possible alternatives below.
                              Simvastatin (Zocor)
                              Used for:
                              $10.65 Lowest GoodRx priceView Prices
                              Used for:
                              $14.40 Lowest GoodRx priceView Prices
                              Used for:
                              $10.28 Lowest GoodRx priceView Prices
                              latest news

                              What is the latest news about Simvastatin (Zocor)?

                              images

                              Simvastatin (Zocor) images

                              Pink Round 02 And A - Simvastatin 20mg Tablet
                              This medicine is Pink, Round Tablet Imprinted With "A" And "02".Pink Round 02 And A - Simvastatin 20mg Tablet
                              Red Oval S 5 - Simvastatin 20mg Tablet
                              This medicine is Red, Oval Tablet Imprinted With "S 5".Red Oval S 5 - Simvastatin 20mg Tablet
                              Orange Oval 20 And B302 - Simvastatin 20mg Tablet
                              This medicine is Orange, Oval Tablet Imprinted With "B302" And "20".Orange Oval 20 And B302 - Simvastatin 20mg Tablet
                              Tan Round 7154 And Tv - Simvastatin 20mg Tablet
                              This medicine is Tan, Round Tablet Imprinted With "Tv" And "7154".Tan Round 7154 And Tv - Simvastatin 20mg Tablet
                              Brown Round 199 And Rdy - Simvastatin 20mg Tablet
                              This medicine is Brown, Round Tablet Imprinted With "Rdy" And "199".Brown Round 199 And Rdy - Simvastatin 20mg Tablet
                              Tan Oval Ll And Co3 - Simvastatin 20mg Tablet
                              This medicine is Tan, Oval Tablet Imprinted With "Co3" And "Ll".Tan Oval Ll And Co3 - Simvastatin 20mg Tablet

                              Get savings updates for Simvastatin (Zocor)

                              Receive price alerts, news, and other messages from GoodRx about Simvastatin (Zocor) and other healthcare topics and relevant savings offers.

                              By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx.

                              Browse medications

                              View All

                              Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.