Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Simvastatin (Zocor) and pitavastatin (Livalo) are both statins used to lower cholesterol, but they have some key differences. Simvastatin is available in a cheaper generic form, while Livalo does not have a generic alternative. Simvastatin is a first-choice medication for lowering cholesterol and reducing the risk of heart attack and stroke, whereas Livalo has not been shown to lower the risk of these events. Livalo may be better for you if you have experienced muscle pain with other statins or have a kidney condition, as it is less likely to cause muscle and kidney damage. Additionally, Livalo has fewer drug interactions, making it a good option if you take multiple medications. Both medications should not be used during pregnancy or breastfeeding, but Livalo is noted for its higher cost if not covered by insurance.
Simvastatin (Zocor)
Pitavastatin calcium (Livalo)
Simvastatin (Zocor)
Pitavastatin calcium (Livalo)
Summary of Simvastatin vs. Livalo
Summary for Statin
Prescription only
Simvastatin (Zocor) is a statin used to lower your cholesterol to help protect your heart and blood vessels from serious, and even life-threatening, medical problems, such as heart attack or stroke. Simvastatin (Zocor) isn't meant to lower cholesterol on its own. Instead, you should take it in addition to eating a healthy diet and having a regular exercise routine. To get the most out of the medication, it's best to take simvastatin (Zocor) nightly before going to sleep.
Summary for Statin
Prescription only
Pitavastatin calcium, also known by its brand name, Livalo, is a moderate-intensity statin for people with high cholesterol. It lowers "bad" cholesterol and triglycerides (fats) and raises "good" cholesterol in the body. Pitavastatin calcium (Livalo) is a tablet that's taken by mouth once per day at any time of day. It's important to follow a heart-healthy diet while taking the medication to get the most benefits from treatment. Side effects include muscle pain, back pain, and constipation. Pitavastatin calcium (Livalo) is available as a brand-name and generic medication.
Indications of Simvastatin vs. Livalo
Indications for
•Prevention of heart or blood vessel problems (e.g., heart attack or stroke) in people at higher-risk for heart problems