Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Simvastatin (Zocor) and pitavastatin (Livalo) are both statins used to lower cholesterol, but they have some key differences. Simvastatin is available in a cheaper generic form, while Livalo does not have a generic alternative. Simvastatin is a first-choice medication for lowering cholesterol and reducing the risk of heart attack and stroke, whereas Livalo has not been shown to lower the risk of these events. Livalo may be better for you if you have experienced muscle pain with other statins or have a kidney condition, as it is less likely to cause muscle and kidney damage. Additionally, Livalo has fewer drug interactions, making it a good option if you take multiple medications. Both medications should not be used during pregnancy or breastfeeding, but Livalo is noted for its higher cost if not covered by insurance.
Simvastatin
Pitavastatin calcium (Livalo)
Simvastatin
Pitavastatin calcium (Livalo)
Summary of Simvastatin vs. Livalo
Summary for Statin
Prescription only
Simvastatin is a low-to-moderate intensity statin that helps lower cholesterol. This helps lower the risk of serious problems like heart attack or stroke. It's approved for adults and certain children 10 years and older. Simvastatin tablets are available as brand-name Zocor and a generic. The liquid suspension form only comes as brand-name FloLipid. The simvastatin dose is taken by mouth once each night. It works best when you also eat heart-healthy foods and stay active. Possible side effects are stomach pain, muscle pain, and headache.
Summary for Statin
Prescription only
Pitavastatin calcium, also known by its brand name, Livalo, is a moderate-intensity statin for people with high cholesterol. It lowers "bad" cholesterol and triglycerides (fats) and raises "good" cholesterol in the body. Pitavastatin calcium (Livalo) is a tablet that's taken by mouth once per day at any time of day. It's important to follow a heart-healthy diet while taking the medication to get the most benefits from treatment. Side effects include muscle pain, back pain, and constipation. Pitavastatin calcium (Livalo) is available as a brand-name and generic medication.