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Gemtesa Coupon - Gemtesa 75mg tablet

Gemtesa

vibegron
Used for Overactive Bladder
Used for Overactive Bladder

Gemtesa is a brand-name medication that's used to treat overactive bladder (OAB) in adults. This includes OAB in people who are taking medications for benign prostatic hyperplasia (BPH). Gemtesa belongs to the drug class called beta-3 adrenergic agonists. The typical dosage is 1 tablet by mouth once per day. Side effects aren't common but can include headache and symptoms of a common cold. There's no generic version available yet.

Reviewed by:
reviewer
Allison Gourley, PharmD
reviewer
Robert Chad Hakim, PharmD, BCCCP
Last reviewed on January 7, 2025
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageCostAlternativesLatest newsImagesReferencesPricesMedicare
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What is Gemtesa?

What is Gemtesa used for?

How Gemtesa works

Gemtesa is a beta-3 adrenergic agonist. It turns on a protein in your bladder called beta-3 adrenergic receptor. This causes your bladder muscles to relax so that your bladder can hold more urine. It helps lessen the need to go to the bathroom as often.

When does Gemtesa start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsGemtesa
Drug ClassBeta-3 adrenergic agonist
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only

More on Gemtesa essentials

Overactive bladder: senior woman at medical appointment 1174322052

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Written by Austin Ulrich, PharmD, BCACP
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$477.86
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What are the side effects of Gemtesa?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Other Side Effects

  • Dry mouth
  • Constipation
  • Trouble emptying the bladder

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Severe allergic reaction: swelling in the lips, face, tongue, or throat; trouble breathing
When do Gemtesa possible side effects begin and end?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Risk of angioedema (swelling of the face, throat, or stomach)
Seek immediate medical care if you experience this side effect.
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

More on Gemtesa side effects

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7 Gemtesa Side Effects and How to Manage Them

Written by Goldina Erowele, PharmD, MBA

The following side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

pros-and-cons

Pros and cons of Gemtesa

thumbs-up

Pros

A first-choice option for overactive bladder

Can take with anticholinergics for OAB, if needed

Tablets are crushable if you have trouble swallowing pills

thumbs-down

Cons

Can take several weeks to see improvement in your symptoms

Not recommended for people with severe liver or kidney problems

Hasn't been studied in children

pharmacist-tips

Pharmacist tips for Gemtesa

pharmacist

  • You can take Gemtesa with or without food.

    • Swallow the Gemtesa tablet whole with a glass of water.

      • If you're having trouble swallowing the tablet whole, you can crush it and mix it with a tablespoon of applesauce. Take the mixture right after mixing it along with a glass of water.

        • Keep in mind that certain foods can irritate the bladder and make your urinary symptoms worse. These foods include alcohol, coffee, carbonated drinks (sodas), spicy foods, and citrus fruits. Work with your care team on a diet plan that meets your needs.

          More on Gemtesa tips

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          faqs

          Frequently asked questions about Gemtesa

          How long does it take for Gemtesa to work?
          Gemtesa can start to work in as early as 2 weeks. But it can take about 3 months to get the full effects of the medication. Talk to your prescriber if you have concerns about how long it takes for Gemtesa to work.
          How long does Gemtesa stay in your system?
          It can take about 6 days for most of Gemtesa to leave your body after a single dose. This time frame is estimated based on the half-life of the medication. But even though the medication can stay in your system for about 6 days, you should still take it once every day. This helps keep the levels of Gemtesa high enough in your body to work well.
          Who shouldn't take Gemtesa?
          People who've previously had a severe allergic reaction to Gemtesa shouldn't take it. A severe allergic reaction can include swelling of the face or mouth or trouble breathing. In addition, speak with your prescriber first if you're taking mirabegron (Myrbetriq). Mirabegron (Myrbetriq) and Gemtesa belong to the same drug class, and taking them together might raise your risk for side effects. Also talk to your prescriber about whether you should continue taking Gemtesa if you have bothersome side effects from the medication.
          Can Gemtesa cause dry eyes?
          Dry eyes isn't a typical side effect of Gemtesa. If you have dry eyes, you can try artificial tears. Contact your optometrist or ophthalmologist (eye specialist) if your dry eyes get too bothersome.
          Does Gemtesa cause hair loss?
          Hair loss wasn't a side effect that people who took Gemtesa reported in clinical trials. Contact your prescriber if you notice unusual hair loss while you're taking Gemtesa. They can examine what's causing this hair loss.
          Does Gemtesa cause fatigue?
          No. People who took Gemtesa during clinical trials didn't report having fatigue or tiredness. Speak with your primary care provider if you feel unusually tired while you're taking this medication.
          Does Gemtesa cause weight gain?
          No, Gemtesa doesn't typically cause weight gain. Let your primary care provider know if you experience unexpected weight gain. They can help figure out the cause.
          Can you take Gemtesa while pregnant or breastfeeding?
          Tell your healthcare team if you're pregnant or breastfeeding. They can discuss with you about the risks and benefits of taking Gemtesa. It's not clear whether this medication is safe for you and your baby. But animal studies show that it isn't expected to cause harm to babies.
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          What are the risks and warnings for Gemtesa?

          Gemtesa can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

          risk-warning

          Angioedema (swelling of face, mouth, throat, or other organ)

          Angioedema (swelling of the face, lips, tongue, throat, or other organs) can happen at any time while you're taking Gemtesa. In more serious cases, swelling of the throat can make it difficult to breathe, which can be life-threatening. Talk to your care team if you have any head or neck swelling that doesn't go away. Get medical help right away if you have serious swelling or difficulty breathing.

          risk-warning

          Risk of difficulty emptying the bladder completely

          • Risk factors: Blockage in the bladder | Use of certain overactive bladder medications

            Some people who took Gemtesa had problems urinating or emptying their bladder completely. The risk might be higher if you have a blockage in your bladder or if you take anticholinergic medications for overactive bladder. Keeping urine in your bladder for long periods of time can lead to complications, such as urinary tract infection (UTI) bladder damage, and kidney damage. Let your prescriber know if you can't urinate or can't empty your bladder fully, even though you feel the urge to urinate.

            dosage

            Gemtesa dosage forms

            The average cost for 30 tablets of 75mg of Gemtesa is $477.86 with a free GoodRx coupon. This is 21.22% off the average retail price of $606.58.
            tablet
            Tablet
            DosageQuantityPrice as low asPrice per unit
            75mg30 tablets$477.86$15.93

            Typical dosing for Gemtesa

            The typical dose is 75 mg by mouth once per day.

            More on Gemtesa dosage forms

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            alternatives

            What are alternatives to Gemtesa?

            There are a number of medications that your doctor can prescribe in place of Gemtesa. Compare a few possible alternatives below.
            Gemtesa
            Used for:
            $477.86 Lowest GoodRx priceView Prices
            Oxybutynin
            Used for:

            • Overactive bladder

            • Incontinence in children due to a neurologic (brain) condition, such as spina bifida

            $8.50 Lowest GoodRx priceView Prices
            Myrbetriq (mirabegron)
            Used for:
            $380.63 Lowest GoodRx priceView Prices
            images

            Gemtesa images

            Green Oval V75 - GEMTESA 75mg Tablet
            This medicine is Green, Oval Tablet Imprinted With "V75".Green Oval V75 - GEMTESA 75mg Tablet
            Green Oval V75 - GEMTESA 75mg Tablet
            This medicine is Green, Oval Tablet Imprinted With "V75".Green Oval V75 - GEMTESA 75mg Tablet

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            References

            Best studies we found

            Cameron, A. P., et al. (2024). The AUA/SUFU guideline on the diagnosis and treatment of idiopathic overactive bladder. The Journal of Urology.

            Fernandez, J. (2024). Angioedema. Merck Manual Consumer Version.

            Frankel, J., et al. (2021). Vibegron improves quality-of-life measures in patients with overactive bladder: Patient-reported outcomes from the EMPOWUR study. International Journal of Clinical Practice.

            View All References (5)

            National Institute of Diabetes and Digestive and Kidney Diseases. (2019). Definition & facts of urinary retention.

            Schena, G., et al. (2019). Everything you always wanted to know about β3-AR * (* but were afraid to ask). Cells.

            Sumitomo Pharma America, Inc. (2024). Gemtesa- vibegron tablet, film coated [package insert]. DailyMed.

            Urology Care Foundation. (2018). 10 foods your bladder will fall in love with.

            Urology Care Foundation. (2024). What is overactive bladder (OAB)?

            GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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