Medications for colon cancer are used to treat cancer in the colon and rectum. They work in various ways to stop cancer cells from growing and spreading. Common classes include antimetabolites, monoclonal antibodies, and tyrosine kinase inhibitors. Antimetabolites like fluorouracil and capecitabine (Xeloda) are usually taken as oral pills or given as injections. Monoclonal antibodies, such as bevacizumab (Zirabev), are given as injections. Tyrosine kinase inhibitors like regorafenib (Stivarga) are taken as oral pills.