Key takeaways
Tirzepatide (Zepbound) and metformin are both medications used to help manage conditions related to weight and blood sugar. Tirzepatide is a GIP and GLP-1 agonist, while metformin is a biguanide. Tirzepatide is FDA-approved for weight loss and sleep apnea in adults, whereas metformin is approved for Type 2 diabetes in people aged 10 and older. Tirzepatide is given as a weekly injection, while metformin is taken orally two to three times a day. Tirzepatide is only available as a brand-name medication, but metformin is available in generic form. Common side effects of tirzepatide include nausea and diarrhea, while metformin often causes diarrhea and nausea as well. Both medications can interact with other diabetes medications, potentially causing low blood sugar. However, tirzepatide may also interact with birth control pills, making them less effective.
