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Zaditor vs. Crolom

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Zaditor (ketotifen) and cromolyn (Crolom) are both eye drops used to treat allergy-related eye symptoms, but they have some key differences. Zaditor is an over-the-counter antihistamine and mast cell stabilizer that works quickly, often within 15 minutes, to relieve itchy eyes. It's suitable for adults and children aged 3 and older and is typically used twice a day. In contrast, cromolyn is a prescription-only mast cell stabilizer that helps with chronic eye allergies, including itching, tearing, and redness. Cromolyn takes longer to start working, often requiring several days to weeks for full effect. It can be used in adults and children as young as 4 years old, and typically used 4 to 6 times a day. While Zaditor shouldn’t be used for more than 3 days in a row, while cromolyn is safe for long-term use. Neither medication should be used with contact lenses due to preservatives that can damage the lenses. Cromolyn is considered a good option for pregnant women, but there isn’t enough information to know whether Zaditor is safe during pregnancy.

Zaditor

(ketotifen)

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Cromolyn

(Gastrocrom)

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Summary for Zaditor

Over-the-counter

Zaditor (ketotifen) is an antihistamine eye drop that's available over the counter for allergy-related itchy eyes. It works by blocking histamine and stopping your body from releasing chemicals that cause allergy symptoms. Adults and children can use Zaditor (ketotifen). The typical dosage is one drop into the affected eye(s) twice daily. Side effects can include headache, blurry vision, and dry eyes.

Indications for Zaditor

  • Allergy-related itchy eyes

Pros and Cons for Zaditor

Pros

  • Works within 15 minutes to relieve itchy eyes
  • Available over the counter
  • Can use in children age 3 or older
  • Only need to use 1 drop twice a day

Cons

  • Won't treat an eye infection
  • Shouldn't be used for irritation caused by contact lenses
  • Can only be used for a short period of time
  • Need to take your contact lens out before placing the eye drop

Common Side Effects for Zaditor

Warnings for Zaditor

  • Not to be used with contact lenses
  • Allergy to ingredients
  • Risk for eye infection

Summary for Crolom

Prescription only

Cromolyn (Gastrocrom) is an oral solution that helps manage mastocytosis, a condition where too many mast cells release chemicals that can cause symptoms like diarrhea, flushing, or itching. It belongs to a drug class called mast cell stabilizers, and works by stopping mast cells from chemicals that cause inflammation. You typically take it 4 times a day by mouth, before meals and at bedtime. Side effects include headache and diarrhea.

Indications for Crolom

Pros and Cons for Crolom

Pros

  • Works by directly targeting mast cells
  • Typically well tolerated with few side effects
  • Safe for children as young as 2 years old

Cons

  • Must be taken up to 4 times a day
  • Can take 2 to 6 weeks to work
  • Needs to be prepared before taking it

Common Side Effects for Crolom

  • Headache (5%)
  • Diarrhea (5%)

Warnings for Crolom

  • Kidney or liver problems
  • Allergic reaction

Prices with our coupons for Zaditor vs. Crolom

Price Card Drug Icon
Ketotifen1 eye dropper / 5ml of 0.025%
$10.65$13.71
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Price Card Drug Icon
Cromolyn1 carton / 96 ampules of 100mg/5ml
$115.50$560.17
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