Key takeaways
Wixela Inhub (fluticasone/salmeterol) and Advair (fluticasone/salmeterol) are both prescription combination inhalers used for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD). They both contain an inhaled corticosteroid (ICS) and a long-acting beta agonist (LABA). However, there are some differences between them. Wixela Inhub is the generic version of Advair Diskus and is available in three strengths: 100 mcg/50 mcg, 250 mcg/50 mcg, and 500 mcg/50 mcg. Advair is available as Advair Diskus and Advair HFA. Advair Diskus form is available in the same three strengths, while the HFA form comes as 45 mcg/21 mcg, 115 mcg/21 mcg, and 230 mcg/21 mcg. Wixela Inhub and Advair Diskus are typically taken as one inhalation twice daily, but Advair HFA requires two puffs twice daily. Common side effects for both include upper respiratory infections, sore throat, and headaches, but Advair HFA users may also experience muscle and bone pain. Both medications can cause oral thrush (a fungal infection), so it's important to rinse your mouth after use.
