Key takeaways
Velphoro (sucroferric oxyhydroxide) and Renvela (sevelamer carbonate) are both phosphate binders used to lower blood phosphate levels in people with chronic kidney disease (CKD) on dialysis. Velphoro is a chewable tablet with a berry flavor, while Renvela is available as a tablet that you swallow whole or as a powder that you can mix with food or drinks. Velphoro must be taken three times a day with meals, and it can cause dark stools and discolored teeth. Renvela also needs to be taken with meals and can cause stomach side effects like nausea, vomiting, and diarrhea. Unlike Velphoro, Renvela is available as a lower-cost generic. Additionally, Renvela can be used in children as young as 6 years old, whereas Velphoro is only for adults. Both medications can interact with other medications, so it's important to tell your provider about all the medications you are taking.
