Key takeaways
Lanthanum (Fosrenol) and Auryxia (ferric citrate) are both phosphate binders used to lower high blood phosphate levels in people with advanced kidney disease. However, they have some key differences. Lanthanum is calcium-free and must be chewed or crushed before swallowing, while Auryxia should be swallowed whole and contains iron, which can also help treat iron deficiency anemia. Because of the iron content, Auryxia can cause dark stools and has a risk of iron overload. Lanthanum can cause digestive tract blockages and may interfere with X-ray results. Both medications need to be taken with meals to work effectively, but Auryxia requires more frequent blood tests to monitor iron levels. Additionally, Lanthanum is available in powder form for those who have trouble chewing tablets, whereas Auryxia is not.
