Key takeaways
Lanthanum (Fosrenol) and Cinacalcet (Sensipar) are both medications used to manage conditions related to kidney disease, but they work in different ways and treat different issues. Lanthanum is a phosphate binder that helps lower phosphorus levels in the blood by binding to phosphates in your food, and it must be taken with meals. Cinacalcet, on the other hand, is a calcimimetic that lowers parathyroid hormone levels, which in turn reduces calcium and phosphorus levels in the blood. Lanthanum is typically taken three times a day, while Cinacalcet is usually taken once or twice daily with food. Lanthanum is available in both tablet and powder forms, whereas Cinacalcet should not be crushed or chewed and is available as a generic medication. Common side effects of Lanthanum include nausea and belly pain, while Cinacalcet can cause nausea, vomiting, and low calcium levels, which can be serious. Both medications require regular blood tests to monitor their effectiveness and safety.
