Key takeaways
Enalapril (Vasotec) and Entresto (sacubitril/valsartan) are both used to treat heart conditions, but they have some key differences. Enalapril is an ACE inhibitor that helps relax blood vessels to lower blood pressure and treat heart failure. It is available in generic form and can be taken once or twice daily. Entresto, on the other hand, is a combination of two medications: sacubitril, a neprilysin inhibitor, and valsartan, an ARB. It is specifically used for heart failure and is taken twice daily. Unlike Enalapril, Entresto is not available as a generic. Both medications can cause side effects like dizziness and cough, as well as low blood pressure and high potassium levels. Additionally, you should not take Entresto if you have taken an ACE inhibitor like Enalapril within the last 36 hours due to the risk of angioedema.
