Compare Trintellix vs. Prozac

Trintellix (vortioxetine) and Prozac (fluoxetine) are both medications used to treat depression, but they belong to different drug classes. Trintellix is an atypical antidepressant, while Prozac is a selective serotonin reuptake inhibitor (SSRI). Trintellix is taken once daily and is not available in a generic form, whereas Prozac can be taken once or twice daily and does have a generic version. Prozac is also approved to treat other conditions like obsessive-compulsive disorder (OCD), bulimia, and panic disorder, while Trintellix is only approved for depression. Both medications can cause side effects like nausea and sexual problems, but Prozac is more likely to cause difficulty sleeping. Additionally, Prozac can take up to two months to show full effects, whereas Trintellix might start working in as little as two weeks but can also take up to a month for full benefits.