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Triazolam vs. Oxazepam

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Triazolam (brand name: Halcion) and oxazepam (former brand name: Serax) are both benzodiazepines, but they are used for different purposes. Triazolam is primarily prescribed for short-term treatment of insomnia, while oxazepam is used to manage short-term anxiety and prevent alcohol withdrawal symptoms. Triazolam is taken once before bedtime, whereas oxazepam is taken 3 to 4 times a day. Triazolam works quickly to help you fall asleep but can cause next-day anxiety, while oxazepam helps control anxiety and withdrawal symptoms but isn't specifically for sleep. Both medications can cause drowsiness and dizziness, but triazolam has a higher risk of unusual sleep behaviors like sleep-driving. Oxazepam is considered safer for people with liver problems and can be used in certain children, unlike triazolam. Both medications carry risks of dependence, misuse, and withdrawal, and neither is recommended during pregnancy.

Triazolam

(Halcion)

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Oxazepam

 

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Summary for Triazolam

Prescription only

Triazolam (Halcion) is used to treat insomnia in adults. It belongs to the drug class called benzodiazepines. The typical dosage is one tablet by mouth before bedtime. This medication helps you sleep, but it should only be used for a short period of time, typically for 7 to 10 days at a time. In addition to sedation (sleepiness), this medication can cause side effects like headaches and dizziness. Like other benzodiazepines, triazolam (Halcion) also has other serious risks and interactions with other medications.

Indications for Triazolam

  • Insomnia (difficulty sleeping) in adults

Pros and Cons for Triazolam

Pros

  • Might start to work within 30 minutes
  • Side effects wear off quickly since it's short-acting
  • Lower-cost generic form available

Cons

Common Side Effects for Triazolam

  • Sleepiness (14%)
  • Headache (10%)
  • Dizziness (8%)
  • Nervousness (5%)
  • Lightheadedness (5%)
  • Problems with coordination or movement (5%)
  • Nausea or vomiting (5%)

Warnings for Triazolam

  • Serious risks when taking triazolam (Halcion) and opioids together
  • Potential for misuse and addiction
  • Physical dependence and withdrawal
  • Unusual behavior while sleeping
  • Changes in thoughts or behavior
  • Effects on driving and concentration
  • Difficulty breathing
  • Harm to unborn baby
  • Interactions with other medications

Summary for Oxazepam

Prescription only

Oxazepam is used to treat short-term anxiety, and it also works well to prevent alcohol withdrawal symptoms. It comes as a capsule that you take 3 or 4 times a day. The most common side effects of oxazepam include drowsiness, dizziness, headache, and vertigo. The brand name version is no longer available, but there's a lower-cost generic version.

Indications for Oxazepam

  • Anxiety
  • Alcohol withdrawal

Pros and Cons for Oxazepam

Pros

  • Lower-cost generic available
  • One of the first-choice treatment options for alcohol withdrawal
  • Can be taken by children as young as 6 years old (although you need to work with your child's provider for dosing if they're younger than 12)
  • A possible option for people with liver problems

Cons

  • Can cause withdrawal symptoms if you stop taking oxazepam suddenly
  • Not known if it's safe to take long-term (e.g., more than 4 months)
  • Can cause low blood pressure, so might not be safe in older adults with heart problems
  • Usually taken multiple times a day

Common Side Effects for Oxazepam

  • Drowsiness
  • Dizziness
  • Vertigo, feeling like the room is spinning
  • Headache

Warnings for Oxazepam

  • Extreme sleepiness, slowed breathing, coma, and death
  • Potential for misuse, dependence, and withdrawal
  • Harm to babies during pregnancy and after delivery

Prices with our coupons for Triazolam vs. Oxazepam

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Triazolam2 tablets / 0.25mg
$6.80$14.20
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Oxazepam60 capsules / 15mg
$25.96$94.99
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