Saxagliptin vs. Sitagliptin for Diabetes Type 2: Important Differences and Potential Risks.

Saxagliptin

(Onglyza)

Januvia

(sitagliptin)

Summary for Saxagliptin

Prescription only

Saxagliptin (Onglyza) is an add-on medication to exercise and a balanced, nutritious diet to improve blood sugar control in adults with Type 2 diabetes. It belongs to the drug class called dipeptidyl peptidase-4 (DPP-4) inhibitors. The saxagliptin (Onglyza) dosage is taken by mouth once daily. Possible side effects include certain infections and headaches. The brand name, Onglyza, is no longer available. But the lower-cost generic version is still available.

Indications for Saxagliptin

Type 2 diabetes in adults

Pros and Cons for Saxagliptin

Pros

Taken once daily (with or without food)
Less likely to cause weight gain (compared to some other diabetes medications)
Very low risk of causing hypoglycemia (low blood sugar) when it's taken by itself

Cons

Doesn't lower A1C and blood sugar levels as well as other diabetes medications
Might raise risk of hospitalization due to heart failure in certain people
Not for treating Type 1 diabetes or diabetic ketoacidosis

Common Side Effects for Saxagliptin

Warnings for Saxagliptin

Pancreas problems
Heart failure
Low blood sugar (hypoglycemia)
Joint pain
Large blisters
Risk of allergic reaction

Summary for Sitagliptin

Prescription only

Januvia (sitagliptin) is a prescription medication that helps lower blood sugar in adults with Type 2 diabetes. It works best when you also follow a balanced diet and exercise regularly. It belongs to the drug class called dipeptidyl peptidase-4 (DPP-4) inhibitors, or gliptins. Januvia (sitagliptin) comes as a tablet you take by mouth once a day. Side effects include stuffy or runny nose and headache. Januvia (sitagliptin) is a brand-name medication only; the generic version isn't available yet.

Indications for Sitagliptin

Type 2 diabetes in adults

Pros and Cons for Sitagliptin

Pros

Taken once a day
Not likely to affect your body weight

Cons

Not for people with Type 1 diabetes
Possible risk of severe joint pain

Common Side Effects for Sitagliptin

Runny or stuffy nose and other symptoms of the common cold (5%)

Warnings for Sitagliptin

Inflammation of the pancreas (pancreatitis)
Risk of heart failure
Sudden kidney problems
Low blood sugar when taken with other diabetes medications
Serious allergic reactions
Joint pain
Severe skin reactions

Prices with our coupons for Saxagliptin vs. Sitagliptin

Saxagliptin30 tablets / 5mg

$45.61$523.88

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Sitagliptin (Januvia)30 tablets / 100mg

$43.67$315.26

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Saxagliptin vs. Sitagliptin

Saxagliptin

Januvia

Summary for Saxagliptin

Indications for Saxagliptin

Pros and Cons for Saxagliptin

Pros

Cons

Common Side Effects for Saxagliptin

Warnings for Saxagliptin

Summary for Sitagliptin

Indications for Sitagliptin

Pros and Cons for Sitagliptin

Pros

Cons

Common Side Effects for Sitagliptin

Warnings for Sitagliptin

Prices with our coupons for Saxagliptin vs. Sitagliptin

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Saxagliptin

Januvia

Summary for Saxagliptin

Indications for Saxagliptin

Pros and Cons for Saxagliptin

Pros

Cons

Common Side Effects for Saxagliptin

Warnings for Saxagliptin

Summary for Sitagliptin

Indications for Sitagliptin

Pros and Cons for Sitagliptin

Pros

Cons

Common Side Effects for Sitagliptin

Warnings for Sitagliptin