Skip to main content

Compare
Provera vs. Danazol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Medroxyprogesterone (Provera) and danazol are both prescription medications, but they serve different purposes and belong to different drug classes. Medroxyprogesterone is a progestin used to regulate menstrual cycles and protect the uterus from damage in postmenopausal women taking estrogen replacement medication. Danazol, on the other hand, is a gonadotropin inhibitor used to treat endometriosis and hereditary angioedema. Medroxyprogesterone is typically taken once a day for a short duration each month, while danazol is taken itwo to three times a day depending on why you are taking it. Danazol is not a first-choice treatment for endometriosis due to its side effects, which include acne, weight gain, and a deeper voice. Additionally, danazol can cause serious issues like liver damage and blood clots. Medroxyprogesterone can also have side effects like spotting and breast tenderness, but it is generally well-tolerated.

Medroxyprogesterone

(Provera)

Get free coupons

Danazol

 

Get free coupons

Summary for Provera

Prescription only

Medroxyprogesterone (Provera) can help make your menstrual cycles more regular. It also helps protect the uterus from harm in people who've gone through menopause and are taking estrogen replacement medications. When taken with estrogen therapy, it has some serious risks that you should consider if you need treatment for a long time.

Indications for Provera

  • Lack of menstrual periods due to hormone imbalance
  • Irregular periods due to hormone imbalance
  • Protection of the uterus in postmenopausal women who are taking estrogen medications

Pros and Cons for Provera

Pros

  • Taken once a day
  • Helps protect the uterus from damage if taking estrogen medications after menopause
  • A good alternative to progesterone (Prometrium) if you have a peanut allergy

Cons

  • Need to remember to take on certain days of the month
  • Can have spotting or breakthrough bleeding, even if you've gone through menopause
  • Shouldn't be used in people with liver problems

Common Side Effects for Provera

  • Spotting or breakthrough bleeding
  • Heavier or lighter periods
  • Breast tenderness
  • Nausea

Warnings for Provera

  • When taken with estrogen medications:
  • Blood clots and their complications (heart attack, stroke)
  • Breast cancer
  • Dementia
  • Uterine and ovarian cancer
  • Vision problems
  • Higher blood pressure and cholesterol levels
  • Swelling (fluid buildup)

Summary for Danazol

Prescription only

Danazol treats endometriosis (a painful condition involving the tissue of your uterus), but it's not a first-choice medication because of the side effects.

Indications for Danazol

  • Endometriosis (extra tissue growth in and around your uterus)
  • Hereditary angioedema (inherited condition that causes swelling in your lips and other body parts)

Pros and Cons for Danazol

Pros

  • Works well to treat the pain caused from endometriosis
  • Medication available in a generic form which may make it more affordable

Cons

  • Can't use during pregnancy
  • Not a cure for endometriosis

Common Side Effects for Danazol

  • Weight gain
  • Acne
  • Swelling
  • Deepening of voice
  • Sweating or flushing

Warnings for Danazol

  • Pregnancy and breastfeeding
  • Risk of blood clots
  • Liver disease
  • Increased pressure in the brain

Prices with our coupons for Provera vs. Danazol

Price Card Drug Icon
Medroxyprogesterone10 tablets / 10mg
$11.26$26.43
Get free coupons
More Information
Price Card Drug Icon
Danazol60 capsules / 200mg
$114.18$473.01
Get free coupons
More Information

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.