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Metaglip vs. Diabeta

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Glipizide/metformin

 

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Glyburide

 

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Summary for Metaglip

Prescription only

Glipizide/metformin combines two diabetes medications into one tablet: glipizide (a sulfonylurea) and metformin (a biguanide). It's approved to treat Type 2 diabetes in adults along with diet and exercise. This medication is typically taken by mouth once or twice a day. Some common side effects of glipizide/metformin can include diarrhea and headache; it isn't likely to cause weight gain or weight loss.

Indications for Metaglip

Pros and Cons for Metaglip

Pros

  • Taken by mouth
  • Combination medication, so more convenient to take
  • Available as a lower-cost generic

Cons

  • Need to take with meals
  • Can't take during pregnancy
  • Not an option for children

Common Side Effects for Metaglip

  • Diarrhea (18%)
  • Headache (13%)
  • Cold or flu infection (10%)
  • Low blood sugar levels (9%)
  • Muscle pain (8%)
  • Nausea, vomiting (8%)
  • Stomach pain (6%)
  • Dizziness (5%)

Warnings for Metaglip

  • Lactic acidosis
  • Possible risk of serious heart problems
  • Low blood sugar levels
  • Low vitamin B12 levels

Summary for Diabeta

Prescription only

Glyburide is taken by mouth to lower blood sugar levels for people who have Type 2 diabetes. This medication isn't meant to be taken alone, but in addition to eating a healthy diet and engaging in regular exercise. Glyburide is typically taken once or twice daily, depending on your dose.

Indications for Diabeta

  • Type 2 diabetes

Pros and Cons for Diabeta

Pros

  • Usually taken only once daily with largest meal
  • Can lower A1C levels by 1.5%
  • Taken by mouth, so good option for people who don't like injections
  • Can be taken with some other blood sugar medications, such as metformin

Cons

  • Risk of low blood sugar (hypoglycemia), especially if you have kidney or liver problems
  • More likely to cause low blood sugar than other blood sugar medications, such as metformin
  • Can cause some weight gain
  • Not approved for Type 1 diabetes

Common Side Effects for Diabeta

  • Feeling bloated
  • Nausea
  • Heartburn

Warnings for Diabeta

  • Low blood sugar (hypoglycemia)
  • Possible risk of heart problems
  • Breakdown of red blood cells

Prices with our coupons for Metaglip vs. Diabeta

Price Card Drug Icon
Glipizide/Metformin180 tablets / 5mg/500mg
$41.98$91.99
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Price Card Drug Icon
Glyburide180 tablets / 5mg
$25.93$70.95
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