Key takeaways
Clonazepam (Klonopin) and alprazolam (Xanax) are both benzodiazepines, but they have some key differences. Clonazepam is approved to treat seizures in both adults and children, and panic disorder in adults, while alprazolam is used for generalized anxiety disorder (GAD) and panic disorder in adults. Clonazepam is typically taken two to three times a day, whereas alprazolam is usually taken three times a day. Both medications can cause drowsiness and memory problems, but clonazepam is less likely to cause rebound anxiety when stopping. Clonazepam is available as an orally disintegrating tablet (ODT) for those who have trouble swallowing, while alprazolam is available in quick-dissolving tablets and liquid form. Both medications carry risks of dependence and withdrawal, and you should avoid alcohol while taking them. Additionally, both medications are not recommended for long-term use due to the risk of dependence and other side effects.
