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Compare Intelence vs. Delavirdine

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Etravirine (Intelence) and delavirdine (Rescriptor) are both medications used to treat HIV infections and belong to the same class of non-nucleoside reverse transcriptase inhibitors (NNRTIs). However, there are several differences between them. Etravirine (Intelence) is currently available as both a brand-name and generic medication, while delavirdine (Rescriptor) is no longer available in the United States. Etravirine is typically prescribed for people who have developed resistance to other HIV medications and is taken twice daily after meals. In contrast, delavirdine was discontinued due to low demand and the availability of newer treatments. Etravirine can cause side effects like changes in cholesterol levels and rash, and it interacts with many other medications. Delavirdine, on the other hand, was discontinued for business reasons rather than safety concerns. Etravirine is still a part of current HIV treatment regimens, whereas delavirdine is not used anymore.

  • Etravirine (Intelence)
    Rescriptor (delavirdine)
  • Etravirine (Intelence)
    Rescriptor (delavirdine)

  • Summary of Intelence vs. Delavirdine

    Summary for HIV ARV
    Prescription only

    Etravirine (Intelence) is a medication that's used as part of an antiretroviral (ARV) therapy to treat human immunodeficiency virus (HIV) infections. It's typically given to people who might've developed resistance to other HIV medications. Etravirine (Intelence) comes as tablets that are swallowed whole or dissolved in liquid for people who have trouble swallowing. Some side effects of this medication are changes in cholesterol levels and rash. Etravirine (Intelence) is available as both a brand-name and generic medication.

    Summary for HIV ART
    Prescription only

    Rescriptor (delavirdine) was one of the first HIV antiretroviral (ARV) medications approved by the FDA. It hasn't been a first choice treatment option for many years, and is no longer available in the United States.

  • Indications of Intelence vs. Delavirdine

    Indications for
    •Treatment of HIV infection in people 2 years of age and older
    Indications for

  • Pros and Cons of Intelence vs. Delavirdine

    Pros and Const for HIV ARV
    Pros
    •Available for people 2 years of age and older who weigh at least 22 lbs
    •Can dissolve tablet with liquid to make it easier for people who have trouble swallowing pills to take
    •No need for dose changes if you're pregnant
    •Might work well for people who didn’t see benefits with other HIV medications in the same class
    Cons
    •Need to take twice daily after meals
    •Interacts with many medications, including some other HIV medications (e.g., Tivicay (dolutegravir), atazanavir (Reyataz))
    •Not an option for people who are just starting HIV treatment
    •Doesn't come in a combination pill
    Pros and Const for HIV ART
    Pros
    Cons

  • Common Side Effects of Intelence vs. Delavirdine

    Common Side Effects for
    •Higher fat levels in the blood (up to 20%)
    •Higher blood sugar levels (up to 15%)
    •Rash (10%)
    •Higher creatine kinase levels in the blood (up to 6%)
    •Abnormal liver lab results (up to 6%)
    •Nerve pain or tingling sensation in hands or feet (4%)

    Note: The side effects listed above are from clinical studies with adults taking etravirine (Intelence) and other HIV medications. Side effects might differ in children.

    Common Side Effects for

  • Warnings of Intelence vs. Delavirdine

    Common Side Effects for
    •Severe skin and allergic reactions
    •Overactive immune system
    •Changes in body fat
    •Interactions with other medications
    Common Side Effects for

  • Prices with our coupons for Intelence vs. Delavirdine

    Learn more about Etravirine
    Learn more about Rescriptor

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