Key takeaways
Indocin (indomethacin) and Tylenol (acetaminophen) are both used to relieve pain, but they work in different ways and are used for different types of pain. Indocin is a prescription-only NSAID that helps reduce inflammation and is used to treat various types of arthritis and shoulder pain. It is also available as a rectal suppository that must be stored in the refrigerator. On the other hand, Tylenol is an over-the-counter analgesic that helps lower fever and relieve mild pain. It comes in many forms, including tablets, liquids, and suppositories, and does not need refrigeration. Unlike Indocin, Tylenol does not reduce inflammation and is generally safer for your stomach and heart but can cause liver damage if taken in high doses or with alcohol. Indocin can cause serious side effects like stomach bleeding, heart attack, and stroke, while Tylenol's main risk is liver damage.
