Key takeaways
Piroxicam (Feldene) and naproxen (Naprosyn) are used to relieve pain and inflammation, but they have a few differences. Piroxicam is typically taken once daily, while naproxen is usually taken 2 to 3 times per day. Piroxicam is available only as a capsule, while naproxen comes in both tablet and liquid suspension forms. Piroxicam is mainly used for osteoarthritis and rheumatoid arthritis. Naproxen has multiple uses, including gout, tendonitis, and menstrual cramps. Both medications can cause serious side effects like stomach bleeding and heart problems, but naproxen is also known to potentially raise blood pressure. Additionally, piroxicam can take months to show full benefits, however, naproxen works faster - within 30 to 60 minutes - for pain relief. Both should be avoided during pregnancy and have similar risks for severe allergic reactions.
