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Compare Feldene vs. Naproxen

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Piroxicam (Feldene) and naproxen (Naprosyn) are used to relieve pain and inflammation, but they have a few differences. Piroxicam is typically taken once daily, while naproxen is usually taken 2 to 3 times per day. Piroxicam is available only as a capsule, while naproxen comes in both tablet and liquid suspension forms. Piroxicam is mainly used for osteoarthritis and rheumatoid arthritis. Naproxen has multiple uses, including gout, tendonitis, and menstrual cramps. Both medications can cause serious side effects like stomach bleeding and heart problems, but naproxen is also known to potentially raise blood pressure. Additionally, piroxicam can take months to show full benefits, however, naproxen works faster - within 30 to 60 minutes - for pain relief. Both should be avoided during pregnancy and have similar risks for severe allergic reactions.

  • Piroxicam (Feldene)
    Naproxen (Naprosyn)
  • Piroxicam (Feldene)
    Naproxen (Naprosyn)

  • Summary of Feldene vs. Naproxen

    Summary for NSAID
    Prescription only

    Piroxicam (Feldene) is a nonsteroidal anti-inflammatory drug (NSAID) that works well to relieve symptoms of arthritis, such as joint pain, swelling, and stiffness. It's a capsule that's taken by mouth, typically once daily. Possible side effects include diarrhea, nausea, vomiting, and rash.

    Summary for NSAID
    Prescription only

    Prescription-strength naproxen (Naprosyn) is a non-steroidal anti-inflammatory drug (NSAID). It can be taken by adults and children to relieve pain and symptoms of certain conditions that cause inflammation, such as rheumatoid arthritis, osteoarthritis, or gout. Naproxen (Naprosyn) works by blocking specific proteins that cause inflammation and pain. Naproxen (Naprosyn) comes as tablet and liquid suspension that are taken by mouth, typically 2 to 3 times per day. Some common side effects include heartburn, stomach pain, and nausea.

  • Indications of Feldene vs. Naproxen

    Indications for
    •Pain from osteoarthritis
    •Pain from rheumatoid arthritis
    Indications for
    •Rheumatoid arthritis (RA)
    •Osteoarthritis (OA)
    •Ankylosing spondylitis (AS) (arthritis of the spine)
    •Polyarticular juvenile idiopathic arthritis (arthritis in children)
    •Tendonitis and bursitis
    •Gout attacks
    •Pain
    •Menstrual cramps

  • Pros and Cons of Feldene vs. Naproxen

    Pros and Const for NSAID
    Pros
    •Can be taken once daily
    •Taken by mouth
    •Available as a lower-cost generic
    Cons
    •Not available as a liquid
    •Can take 2 to 3 months to get the full effects
    •Can cause serious complications, including stomach bleeding and kidney problems, if taken for a long period of time.
    Pros and Const for NSAID
    Pros
    •Works well for treating pain and inflammation
    •Effects last longer than other NSAIDs, such as ibuprofen (Advil)
    •Available as a liquid for people who have a hard time swallowing pills
    Cons
    •Can cause stomach bleeding or stomach ulcers
    •Not safe to take after 20 weeks of pregnancy
    •Might not be the best option if you're 65 years or older, or have kidney, heart, liver, or bleeding problems

  • Common Side Effects of Feldene vs. Naproxen

    Common Side Effects for
    •Nausea and vomiting
    •Constipation
    •Passing gas
    •Stomach pain
    •Diarrhea
    •Headache
    •Dizziness
    •Swelling or fluid buildup
    •Rash
    •Ringing in the ears

    Please note: The side effects below were reported by up to 10% of people who took piroxicam (Feldene) in clinical trials.

    Common Side Effects for

    The following side effects were reported in 3-9% of people in clinical studies:

    •Heartburn
    •Stomach pain
    •Constipation
    •Nausea
    •Dizziness
    •Drowsiness
    •Headache
    •Itchy skin
    •Bruising
    •Ringing in the ears
    •Swelling
    •Shortness of breath

  • Warnings of Feldene vs. Naproxen

    Common Side Effects for
    •Heart attack and stroke
    •Stomach bleeding and ulcers
    •High blood pressure and heart failure
    •Kidney damage and high potassium levels
    •Liver damage
    •Severe allergic reactions
    •Not for use in pregnant or breastfeeding females
    Common Side Effects for
    •Stomach bleeding
    •Heart attack and stroke
    •High blood pressure and heart failure
    •Kidney damage
    •Liver problems
    •Severe allergic reactions
    •Not for use in pregnant or breastfeeding females

  • Prices with our coupons for Feldene vs. Naproxen

    Learn more about Piroxicam
    Learn more about Naproxen

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