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Compare Feldene vs. Tylenol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Piroxicam (Feldene) and acetaminophen (Tylenol) are both used to relieve pain, but they work differently and are used for different types of pain. Piroxicam is a prescription nonsteroidal anti-inflammatory drug (NSAID) that helps with arthritis pain by reducing inflammation (swelling). Acetaminophen isn't typically used to reduce inflammation, but it's available over-the-counter (OTC) to help lower fever and relieve mild pain. Piroxicam is taken once daily and can take up to 2-3 months to feel the full effects, whereas acetaminophen works within 45 minutes and is taken every 4-6 hours as needed. Piroxicam can cause serious side effects like stomach bleeding and heart problems, especially if taken for a long time, while acetaminophen's main risk is liver damage, particularly if you drink alcohol or take too much. Piroxicam isn't recommended in people who are pregnant; however, acetaminophen is generally considered safe during pregnancy and breastfeeding.

  • Piroxicam (Feldene)
    Acetaminophen (Tylenol)
  • Piroxicam (Feldene)
    Acetaminophen (Tylenol)

  • Summary of Feldene vs. Tylenol

    Summary for NSAID
    Prescription only

    Piroxicam (Feldene) is a nonsteroidal anti-inflammatory drug (NSAID) that works well to relieve symptoms of arthritis, such as joint pain, swelling, and stiffness. It's a capsule that's taken by mouth, typically once daily. Possible side effects include diarrhea, nausea, vomiting, and rash.

    Summary for Analgesic

    Acetaminophen (Tylenol) is an over-the-counter (OTC) medication used to lower fever and relieve mild pain in adults and children. It's available in many strengths and formulations, such as tablets, chewable tablets, and liquid. In general, acetaminophen (Tylenol) works within 45 minutes when it's taken by mouth. This medication typically doesn't have many side effects. It's recommended to limit or avoid alcohol while taking acetaminophen (Tylenol) to lower your risk for liver problems.

  • Indications of Feldene vs. Tylenol

    Indications for
    •Pain from osteoarthritis
    •Pain from rheumatoid arthritis
    Indications for
    •Mild pain
    •Fever

  • Pros and Cons of Feldene vs. Tylenol

    Pros and Const for NSAID
    Pros
    •Can be taken once daily
    •Taken by mouth
    •Available as a lower-cost generic
    Cons
    •Not available as a liquid
    •Can take 2 to 3 months to get the full effects
    •Can cause serious complications, including stomach bleeding and kidney problems, if taken for a long period of time.
    Pros and Const for Analgesic
    Pros
    •Works well to relieve mild aches or pain and lower fever
    •Can use in adults and children
    •Available in a lower-cost generic and is available over the counter
    •Comes in many different strengths and forms (e.g., tablet, capsule, chewable tablet, liquid, powder, suppository)
    Cons
    •Doesn't help with inflammation and swelling
    •Might not work as well to treat moderate-to-severe pain
    •Not the best option for people who drink alcohol often because of the risk of liver damage

  • Common Side Effects of Feldene vs. Tylenol

    Common Side Effects for
    •Nausea and vomiting
    •Constipation
    •Passing gas
    •Stomach pain
    •Diarrhea
    •Headache
    •Dizziness
    •Swelling or fluid buildup
    •Rash
    •Ringing in the ears

    Please note: The side effects below were reported by up to 10% of people who took piroxicam (Feldene) in clinical trials.

    Common Side Effects for

    Side effects typically aren't common with this medication.

  • Warnings of Feldene vs. Tylenol

    Common Side Effects for
    •Heart attack and stroke
    •Stomach bleeding and ulcers
    •High blood pressure and heart failure
    •Kidney damage and high potassium levels
    •Liver damage
    •Severe allergic reactions
    •Not for use in pregnant or breastfeeding females
    Common Side Effects for
    •Liver damage
    •Accidental overdose
    •Allergic skin reactions

  • Prices with our coupons for Feldene vs. Tylenol

    Learn more about Piroxicam
    Learn more about Acetaminophen

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