Key takeaways
Indocin (indomethacin) and Feldene (piroxicam) are both NSAIDs used to treat arthritis, but they have some key differences. Indocin is available as a tablet, suspension, and rectal suppository, while Feldene is taken orally as a capsule. Indocin is typically used multiple times a day, whereas Feldene is usually taken once daily. Indocin treats a wider range of conditions, including gouty arthritis and shoulder pain, while Feldene is mainly for osteoarthritis and rheumatoid arthritis. Both medications can cause serious side effects like stomach bleeding and heart problems, but Indocin has additional risks such as worsening mental health issues. Both are available as lower-cost generics.
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