Key takeaways
Diclofenac (Voltaren) and indomethacin (Indocin) are both NSAIDs used to treat pain and inflammation, but they have some key differences. Diclofenac is available in various forms, including tablets, capsules, and powder, and is used for conditions like osteoarthritis, rheumatoid arthritis, and migraines. Indomethacin, on the other hand, is available as a capsule or rectal suppository and is used for more severe conditions like gouty arthritis and shoulder bursitis or tendonitis. Both medications should be taken with food, and indomethacin suppositories need to be refrigerated and moistened before use. Neither medication is available over-the-counter and both require a prescription. Both medications carry risks of serious side effects like heart attack, stroke, and stomach bleeding, but indomethacin also has warnings about worsening mental health conditions and nervous system problems.
