Key takeaways
Ibuprofen (Advil, Motrin) and diclofenac (Cambia, Zipsor) are both nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat pain and inflammation. They are similar in that they both help with conditions like osteoarthritis, rheumatoid arthritis, and menstrual cramps. However, ibuprofen is available over-the-counter and by prescription, while diclofenac is only available by prescription. Ibuprofen comes in various forms, including tablets, capsules, and liquid, and is typically taken every 4 to 8 hours. Diclofenac, on the other hand, is available in delayed-release tablets, extended-release tablets, capsules, and powder packets, with dosing varying based on the formulation and condition being treated. Common side effects of both medications include nausea, heartburn, and stomach pain. They also carry risks of serious side effects, such as heart attack, stroke, and stomach bleeding, especially with long-term use. You should not take ibuprofen and diclofenac together, as this increases the risk of severe side effects. Always consult your healthcare team before starting or combining these medications.
