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Ibuprofen vs. Coumadin

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that's used to temporarily relieve fever, pains, and aches in adults and children. In general, ibuprofen is taken by mouth every 4 to 8 hours, though the dosage depends on your age, weight, and other medical problems. Ibuprofen side effects include nausea, heartburn, and stomach pain, but taking it with food might help prevent these side effects. Ibuprofen is available over the counter and by prescription, depending on the strength you need.

Over-the-counter ibuprofen:

• Short-term relief of minor aches and pains due to headache, muscle aches, minor arthritis pain, toothache, backache, the common cold, or menstrual cramps
• Fever

Prescription ibuprofen:

• Mild-to-moderate pain
• Pain from rheumatoid arthritis (RA) or osteoarthritis (OA)
• Pain from menstrual cramps

The following side effects were reported in up to 9% of people in clinical studies.

• Nausea
• Stomach pain
• Heartburn
• Dizziness
• Rash

• Stomach bleeding and ulcers
• Heart attack and stroke
• High blood pressure and heart failure
• Kidney damage
• Liver problems
• Severe allergic reactions
• Harm to unborn babies
• Caution use in people with phenylketonuria (PKU) - chewable tablets only

Warfarin (Coumadin) is a blood thinner (anticoagulant). It's used to prevent and treat blood clots in adults and children with conditions such as deep vein thrombosis (DVT) or pulmonary embolism (PE). Warfarin (Coumadin) is taken by mouth, typically once daily. Your provider will adjust the dose based on your international normalized ratio (INR). Taking too much warfarin (Coumadin) can lead to side effects like bruising and serious bleeding. If needed, your provider can give you an antidote to reverse the effects of warfarin (Coumadin).

• Prevention and treatment blood clots in the veins
• Prevention and treatment blood clots linked to atrial fibrillation (AFib) or heart valve replacement
• Prevention of more blood clots and to lower risk of death after a heart attack

• Bleeding
• Bruising

• Severe or life-threatening bleeding
• Risk of blood clots from stopping too early
• Risk of fat-containing clots
• Calcium build-up in blood vessels (calciphylaxis)
• Skin or tissue death and risk of gangrene
• Not for use during pregnancy