Key takeaways
Meloxicam and indomethacin (Indocin) are both non-steroidal anti-inflammatory drugs (NSAIDs) used to treat pain and inflammation from conditions like arthritis. They work by blocking proteins called cyclooxygenase (COX) that cause inflammation, pain, and swelling. However, these medications differ in their forms and specific uses. Meloxicam is available in oral forms like capsules, tablets, and liquid, as well as an injectable form (only administered by a healthcare professional), while indomethacin is available as an oral capsulin, oral liquid solution, or rectal suppository. Meloxicam is used for osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis, and its injectable form is for moderate-to-severe pain. Indomethacin treats moderate-to-severe rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, shoulder pain, and gouty arthritis. Meloxicam is typically taken once daily, whereas indomethacin is often taken multiple times a day. Both medications can cause stomach bleeding and should not be taken with other NSAIDs. Common side effects of meloxicam and indomethacin include diarrhea and joint pain, headache, and stomach upset.
