Key takeaways
Indomethacin (Indocin) and meloxicam are both non-steroidal anti-inflammatory drugs (NSAIDs) used to treat pain and inflammation from conditions like arthritis. They work by blocking proteins called cyclooxygenase (COX) that cause inflammation, pain, and swelling. Indomethacin is available as a oral capsules, oral liquid suspension, and rectal suppositories. Meloxicam is available in oral forms like capsules, tablets, and liquid, as well as an injectable form (administered only by a healthcare professional). Indomethacin is typically taken multiple times a day, whereas meloxicam is usually taken once daily. Both medications require a prescription and are available as generics. Common side effects of indomethacinm and meloxicam include headache, stomach upset, and diarrhea. You should avoid taking other NSAIDs with either medication, as this can increase the risk of side effects like stomach bleeding and kidney damage.
