Key takeaways
Etodolac (formerly known as Lodine) and Celecoxib (Celebrex) are prescription non-steroidal anti-inflammatory drugs (NSAIDs). Both are used to treat pain and inflammation, however, they have several differences between them. Etodolac is available only as a generic and comes in immediate-release and extended-release forms. Celecoxib is available as both a brand (Celebrex) and a lower-cost generic. Etodolac can cause stomach issues and is not recommended for people with certain health conditions. Unlike etodolac, celecoxib has fewer stomach problems and is also used to treat a wider range of conditions, including ankylosing spondylitis and menstrual cramps. Children as young as 2 years old can take celecoxib for certain conditions, while the extended-release form of etodolac is safe for children who are at least 6 years of age. Both medications carry risks of heart attack, stroke, and stomach bleeding, but Celecoxib has a lower risk of causing stomach ulcers. You should avoid alcohol with both medications to reduce the risk of stomach bleeding.
