Lodine vs. Celecoxib for Rheumatoid Arthritis and Osteoarthritis: Important Differences and Potential Risks.

Etodolac

Celebrex

(celecoxib)

Summary for Lodine

Prescription only

Etodolac, also known by its brand name Lodine, is a non-steroidal anti-inflammatory drug (NSAID). The immediate-release pills are taken throughout the day; they're approved for adults with sudden, short-term pain; rheumatoid arthritis; or osteoarthritis. There's also an extended-release tablet for people ages 6 years and older that's taken once per day for the same types of arthritis. Side effects can include stomach pain, dizziness, and rash. Etodolac is currently available by prescription as generic only; the brand name has been discontinued.

Indications for Lodine

Osteoarthritis (OA)
Rheumatoid arthritis (RA)
Juvenile idiopathic arthritis - extended-release only
Short-term pain - immediate-release only

Pros and Cons for Lodine

Pros

Works well to treat pain and inflammation
Extended-release tablets can be used for children as young as 6 years old
Available as a lower-cost generic

Cons

Only available as pills that can't be split, open, or crushed
Not safe to take after 20 weeks of pregnancy
Might not be the best option if you're 65 years or older or if you have kidney, heart, liver, or bleeding problems

Common Side Effects for Lodine

The following side effects were reported in 1% to 10% of people who took etodolac:

Stomach pain
Indigestion or heartburn
Nausea
Vomiting
Constipation
Diarrhea
Passing gas
Stomach ulcer
Stomach bleeding
Swelling
Headache
Ringing in the ears
Itching
Rash
Anemia (low red blood cell count)
Elevated liver enzymes

Warnings for Lodine

Stomach bleeding
Heart attack and stroke
High blood pressure and heart failure
Kidney damage
Liver problems
Severe allergic reactions and skin reactions
Not safe to take while pregnant
Risk for bleeding

Summary for Celecoxib

Prescription only

Celecoxib, also known by the brand name Celebrex, is a prescription pain medication that's used to temporarily relieve aches and pains from certain conditions, such as different types of arthritis. Celebrex (celecoxib) is a non-steroidal anti-inflammatory drug (NSAID), but it has a lower risk of causing stomach upset than other medications in its drug class, such as naproxen. The dosage for Celebrex (celecoxib) is typically once or twice a day. It's recommended to avoid taking this medication with alcohol since it can raise your risk for stomach bleeding. Other side effects include headache, indigestion, and diarrhea.

Indications for Celecoxib

Osteoarthritis (OA)
Rheumatoid arthritis (RA)
Juvenile rheumatoid arthritis (JRA)
Ankylosing spondylitis (AS)
Sudden pain
Menstrual cramps

Pros and Cons for Celecoxib

Pros

Can use for different types of arthritis
Fewer stomach side effects compared to some other NSAIDs
Safe to take for children 2 years and older with RA
Can open capsules and mix contents with applesauce, so it's convenient for people with difficulty swallowing pills

Cons

Can raise the risk of heart attack and stroke
Not recommended during second and third trimesters of pregnancy
Not recommended for use if you have severe liver disease
Might not be safe for people with a sulfa allergy

Common Side Effects for Celecoxib

Adults

Headache (16%)
Indigestion (9%)
Upper respiratory infection (8%)
Diarrhea (6%)
Sinus infection (congestion, runny nose; 5%)
Belly pain (4%)

Children

Headache (13%)
Fever (8%)
Belly pain (4-8%)
Cough (7%)
Nausea (7%)
Diarrhea (5%)
Common cold (stuffy nose, sneezing; 5%)

Warnings for Celecoxib

Heart attack and stroke
Stomach bleeding and ulcers
Liver problems
High blood pressure and heart failure
Kidney damage and high potassium levels
Severe allergic reactions
Severe asthma attack
Harm to unborn babies

Prices with our coupons for Lodine vs. Celecoxib

Etodolac60 tablets / 400mg

$25.84$78.79

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Celecoxib30 capsules / 200mg

$11.21$190.99

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Lodine vs. Celecoxib

Etodolac

Celebrex

Summary for Lodine

Indications for Lodine

Pros and Cons for Lodine

Pros

Cons

Common Side Effects for Lodine

Warnings for Lodine

Summary for Celecoxib

Indications for Celecoxib

Pros and Cons for Celecoxib

Pros

Cons

Common Side Effects for Celecoxib

Warnings for Celecoxib

Prices with our coupons for Lodine vs. Celecoxib

Compare other Rheumatoid Arthritis and Osteoarthritis drugs

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Etodolac

Celebrex

Summary for Lodine

Indications for Lodine

Pros and Cons for Lodine

Pros

Cons

Common Side Effects for Lodine

Warnings for Lodine

Summary for Celecoxib

Indications for Celecoxib

Pros and Cons for Celecoxib

Pros

Cons

Common Side Effects for Celecoxib

Warnings for Celecoxib