Key takeaways
Etodolac (formerly known as Lodine) and Arthrotec (diclofenac/misoprostol) are medications used to treat pain and inflammation. Both are only available with a prescription, but they have several differences between them. Etodolac is available only in generic form and is used for conditions like osteoarthritis, rheumatoid arthritis, and short-term pain. Arthrotec, on the other hand, is a combination medication that not only treats arthritis pain but also helps protect the stomach from ulcers caused by medications like etodolac. This makes it particularly useful for people at high risk of stomach and intestinal ulcers. Arthrotec is only approved for use in non-pregnant adults, while etodolac isn't safe for use after 20 weeks of pregnancy. Etodolac is available in an extended-release form allowing for once daily dosing, unlike Arthrotec which must be taken mutliple times daily.
