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Compare Duexis vs. Mobic

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Ibuprofen / famotidine and meloxicam are both medications used to treat arthritis pain, but they belong to different classes. Ibuprofen / famotidine is a combination of a non-steroidal anti-inflammatory drug (NSAID) and a histamine H2 antagonist, while meloxicam is solely an NSAID. Both medications help with osteoarthritis and rheumatoid arthritis, but ibuprofen / famotidine also includes famotidine to help reduce the risk of stomach ulcers. Ibuprofen / famotidine is taken as a tablet three times a day, whereas meloxicam is typically taken once daily and is available in various forms, including oral tablets and capsules, oral suspension, and an injection (administered by a healthcare professional only). Both medications are available as lower-cost generics. Ibuprofen / famotidine used to be available as brand-name Duexis, but this product was discontinued. Common side effects of ibuprofen / famotidine include nausea and high blood pressure, while meloxicam may cause diarrhea and joint pain. Both medications can increase the risk of stomach bleeding, heart attack, and stroke.

  • Duexis (ibuprofen / famotidine)
    Meloxicam
  • Duexis (ibuprofen / famotidine)
    Meloxicam

  • Summary of Duexis vs. Mobic

    Summary for NSAID / Histamine H2 antagonist
    Prescription only

    Duexis is a prescription medication that contains ibuprofen (a non-steroidal anti-inflammatory drug (NSAID)) and famotidine (a H2 blocker). It's taken by adults to treat osteoarthritis (OA) and rheumatoid arthritis (RA), while also helps protect against stomach ulcer. This medication is taken by mouth three times per day. Side effects include headache, nausea, and high blood pressure. Brand name Duexis has been discontinued; this medication is only available as a generic.

    Summary for NSAID
    Prescription only

    Meloxicam is a prescription non-steroidal anti-inflammatory drug (NSAID) used for different types of arthritis pain. It comes as a capsule, tablet, or liquid that you take by mouth. It's also available as an injection that's given by a healthcare provider in a hospital setting. Common side effects include diarrhea, joint pain, and stomach upset. Like all NSAIDs, meloxicam can raise the risk for stomach bleeds.

  • Indications of Duexis vs. Mobic

    Indications for
    •Treatment of osteoarthritis (OA) and rheumatoid arthritis (RA) in adults, while lowering the risk of stomach ulcers
    Indications for
    •Pain from osteoarthritis (capsules, tablets, and oral suspension)
    •Pain from rheumatoid arthritis and juvenile rheumatoid arthritis (JRA) (tablets and oral suspension)
    •Moderate-to-severe pain (Anjeso injection)

  • Pros and Cons of Duexis vs. Mobic

    Pros and Const for NSAID / Histamine H2 antagonist
    Pros
    •Taken by mouth
    •Famotidine helps protect against stomach ulcers
    •Can be stored at room temperature
    Cons
    •Taken 3 times a day
    •Can't be crushed and doesn't come as a liquid; not a good choice for people who can't swallow tablets
    •Not safe for people with certain medical conditions, such as heart problems or kidney problems
    Pros and Const for NSAID
    Pros
    •Only taken once a day
    •Available as a lower-cost generic
    •Causes less stomach upset than some other NSAIDs
    •Works well to treat pain caused by different types of arthritis
    Cons
    •Available only by prescription
    •Not safe during pregnancy
    •Might not be the best option if you're 65 years or older, or have kidney, heart, liver, or bleeding problems
    •Different formulations (e.g., capsules, liquid) might not be able to be substituted for one another

  • Common Side Effects of Duexis vs. Mobic

    Common Side Effects for
    •Nausea (6%)
    •Upset stomach or indigestion (5%)
    •Diarrhea (5%)
    •Constipation (4%)
    •Upper respiratory tract infection (4%)
    Common Side Effects for

    Meloxicam capsules, tablets, and oral solution:

    •Headache (up to 8%)
    •Diarrhea (up to 8%)
    •Joint pain (up to 6%)
    •Urinary tract infections (up to 6%)
    •Flu-like symptoms (up to 6%)
    •Upset stomach (up to 5%)
    •Swelling (up to 5%)

    Meloxicam (Anjeso) injection:

    •Constipation (8%)
    •Liver damage (3%)
    •Low red blood cells (2%)

  • Warnings of Duexis vs. Mobic

    Common Side Effects for
    •Stomach bleeding and ulcers
    •Heart attack and stroke
    •High blood pressure, heart failure, and swelling
    •Kidney damage and high potassium levels
    •Liver problems
    •Severe allergic reactions
    •Harm to unborn babies
    •Accidentally taking too much medication
    •Changes in vision
    Common Side Effects for
    •Stomach bleeding
    •Heart attack and stroke
    •High blood pressure and heart failure
    •Liver problems
    •Kidney damage and high potassium levels
    •Severe allergic reactions
    •Severe asthma attack
    •Harm to unborn babies

  • Prices with our coupons for Duexis vs. Mobic

    Learn more about Duexis
    Learn more about Meloxicam

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