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Compare Duexis vs. Mobic

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Ibuprofen / famotidine and meloxicam are both medications used to treat arthritis pain, but they belong to different classes. Ibuprofen / famotidine is a combination of a non-steroidal anti-inflammatory drug (NSAID) and a histamine H2 antagonist, while meloxicam is solely an NSAID. Both medications help with osteoarthritis and rheumatoid arthritis, but ibuprofen / famotidine also includes famotidine to help reduce the risk of stomach ulcers. Ibuprofen / famotidine is taken as a tablet three times a day, whereas meloxicam is typically taken once daily and is available in various forms, including oral tablets and capsules, oral suspension, and an injection (administered by a healthcare professional only). Both medications are available as lower-cost generics. Ibuprofen / famotidine used to be available as brand-name Duexis, but this product was discontinued. Common side effects of ibuprofen / famotidine include nausea and high blood pressure, while meloxicam may cause diarrhea and joint pain. Both medications can increase the risk of stomach bleeding, heart attack, and stroke.

  • Duexis (ibuprofen / famotidine)
    Meloxicam
  • Duexis (ibuprofen / famotidine)
    Meloxicam

  • Summary of Duexis vs. Mobic

    Summary for NSAID / Histamine H2 antagonist
    Prescription only

    Duexis is a prescription medication that contains ibuprofen (a non-steroidal anti-inflammatory drug (NSAID)) and famotidine (a H2 blocker). It's taken by adults to treat osteoarthritis (OA) and rheumatoid arthritis (RA), while also helps protect against stomach ulcer. This medication is taken by mouth three times per day. Side effects include headache, nausea, and high blood pressure. Brand name Duexis has been discontinued; this medication is only available as a generic.

    Summary for NSAID
    Prescription only

    Meloxicam is a prescription non-steroidal anti-inflammatory drug (NSAID). It's used for different types of arthritis pain. It comes as capsules, tablets and a liquid. All forms are for adults, but some are also for children of certain age and weight. Meloxicam is taken by mouth once a day. The dosage depends on your arthritis type, the form of meloxicam you're using, and age and weight for children. Common side effects include diarrhea, joint pain, and stomach upset. Like all NSAIDs, it can raise the risk of stomach bleeds. Meloxicam is a generic medication; its brand name Mobic is no longer available.

  • Indications of Duexis vs. Mobic

    Indications for
    •Treatment of osteoarthritis (OA) and rheumatoid arthritis (RA) in adults, while lowering the risk of stomach ulcers
    Indications for
    •Osteoarthritis (OA) - capsules, tablets, and oral liquid
    •Rheumatoid arthritis (RA) - tablets and oral liquid
    •Juvenile rheumatoid arthritis (JRA) - tablets and oral liquid

  • Pros and Cons of Duexis vs. Mobic

    Pros and Const for NSAID / Histamine H2 antagonist
    Pros
    •Taken by mouth
    •Famotidine helps protect against stomach ulcers
    •Can be stored at room temperature
    Cons
    •Taken 3 times a day
    •Can't be crushed and doesn't come as a liquid; not a good choice for people who can't swallow tablets
    •Not safe for people with certain medical conditions, such as heart problems or kidney problems
    Pros and Const for NSAID
    Pros
    •Only taken once a day
    •Might cause less stomach upset and other stomach problems than some other NSAIDs
    •Also available as a liquid for people who have trouble swallowing pills
    Cons
    •Available by prescription only
    •Might not be the best option for older adults or people with kidney, heart, liver, or bleeding problems
    •Can't switch easily between capsules, tablets, and liquid (can't be substituted for one another)

  • Common Side Effects of Duexis vs. Mobic

    Common Side Effects for
    •Nausea (6%)
    •Upset stomach or indigestion (5%)
    •Diarrhea (5%)
    •Constipation (4%)
    •Upper respiratory tract infection (4%)
    Common Side Effects for
    •Headache
    •Diarrhea
    •Indigestion
    •Nausea
    •Stomach pain
    •Joint pain
    •Flu-like symptoms

  • Warnings of Duexis vs. Mobic

    Common Side Effects for
    •Stomach bleeding and ulcers
    •Heart attack and stroke
    •High blood pressure, heart failure, and swelling
    •Kidney damage and high potassium levels
    •Liver problems
    •Severe allergic reactions
    •Harm to unborn babies
    •Accidentally taking too much medication
    •Changes in vision
    Common Side Effects for
    •Risk of stomach ulcers and stomach bleeding
    •Risk of heart attack and stroke
    •High blood pressure
    •Swelling and risk of heart failure
    •Liver problems
    •Kidney damage
    •High potassium levels
    •Risk of general bleeding and anemia
    •Severe allergic reactions and skin reactions
    •Worsening asthma in certain people
    •Harm to an unborn baby

  • Prices with our coupons for Duexis vs. Mobic

    Learn more about Duexis
    Learn more about Meloxicam

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