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Compare Duexis vs. Vimovo

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Duexis (ibuprofen / famotidine)
    Vimovo (naproxen / esomeprazole)
  • Duexis (ibuprofen / famotidine)
    Vimovo (naproxen / esomeprazole)

  • Summary of Duexis vs. Vimovo

    Summary for NSAID / Histamine H2 antagonist
    Prescription only

    Duexis is a prescription medication that contains ibuprofen (a non-steroidal anti-inflammatory drug (NSAID)) and famotidine (a H2 blocker). It's taken by adults to treat osteoarthritis (OA) and rheumatoid arthritis (RA), while also helps protect against stomach ulcer. This medication is taken by mouth three times per day. Side effects include headache, nausea, and high blood pressure. Brand name Duexis has been discontinued; this medication is only available as a generic.

    Summary for NSAID / PPI
    Prescription only

    Vimovo (naproxen / esomeprazole) is a combination medication for people age 12 years and older who have arthritis. It contains naproxen, a nonsteroidal anti-inflammatory drug (NSAID) that relieves arthritis symptoms like joint pain and swelling. This combination medication also contains the proton pump inhibitor (PPI) esomeprazole to protect against damage to the stomach from naproxen. Vimovo (naproxen / esomeprazole) is a tablet that's taken by mouth twice a day. Side effects can include inflammation of the stomach lining and diarrhea.

  • Indications of Duexis vs. Vimovo

    Indications for
    •Treatment of osteoarthritis (OA) and rheumatoid arthritis (RA) in adults, while lowering the risk of stomach ulcers
    Indications for
    •Treatment of different kinds of arthritis while lowering the risk for stomach ulcers
    •Osteoarthritis (OA) in adults
    •Rheumatoid arthritis (RA) in adults
    •Ankylosing spondylitis (AS) in adults
    •Arthritis in children 12 years and older (juvenile idiopathic arthritis, JIA)

  • Pros and Cons of Duexis vs. Vimovo

    Pros and Const for NSAID / Histamine H2 antagonist
    Pros
    •Taken by mouth
    •Famotidine helps protect against stomach ulcers
    •Can be stored at room temperature
    Cons
    •Taken 3 times a day
    •Can't be crushed and doesn't come as a liquid; not a good choice for people who can't swallow tablets
    •Not safe for people with certain medical conditions, such as heart problems or kidney problems
    Pros and Const for NSAID / PPI
    Pros
    •Works well to relieve pain and swelling from arthritis
    •Helps protect against stomach irritation and ulcers from naproxen without needing to take another pill
    Cons
    •Must take twice a day, each time at least 30 minutes before a meal
    •Has many serious risks from both naproxen and esomeprazole ingredients
    •Less flexible for dose adjustments since it's a fixed combination of two ingredients

  • Common Side Effects of Duexis vs. Vimovo

    Common Side Effects for
    •Nausea (6%)
    •Upset stomach or indigestion (5%)
    •Diarrhea (5%)
    •Constipation (4%)
    •Upper respiratory tract infection (4%)
    Common Side Effects for
    •Inflammation of the stomach lining, leading to symptoms like stomach pain, nausea, and loss of appetite (gastritis, 17%)
    •Diarrhea (6%)

  • Warnings of Duexis vs. Vimovo

    Common Side Effects for
    •Stomach bleeding and ulcers
    •Heart attack and stroke
    •High blood pressure, heart failure, and swelling
    •Kidney damage and high potassium levels
    •Liver problems
    •Severe allergic reactions
    •Harm to unborn babies
    •Accidentally taking too much medication
    •Changes in vision
    Common Side Effects for
    •Heart attack or stroke
    •Stomach bleeding and ulcers
    •Liver damage
    •High blood pressure, heart failure, and fluid buildup in the body
    •Kidney damage
    •Severe allergic reaction or skin reaction
    •Abnormal nutrient and electrolyte levels
    •Bone fracture
    •Lupus
    •Harm to unborn baby

  • Prices with our coupons for Duexis vs. Vimovo

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    Learn more about Vimovo

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