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Foundayo vs. Mounjaro

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Foundayo

(orforglipron)

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Mounjaro

(tirzepatide)

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Summary for Foundayo

Prescription only

Foundayo (orforglipron) is an oral glucagon-like peptide-1 (GLP-1) receptor agonist. It's approved for weight loss in certain adults. This medication is meant to be used together with a reduced-calorie diet and exercise. Foundayo (orforglipron) comes as tablets and is taken by mouth once a day with or without food. The dose is slowly raised over several weeks. Common side effects include nausea, constipation, and diarrhea.

Indications for Foundayo

Pros and Cons for Foundayo

Pros

  • A pill that's taken once a day at any time of day
  • Can take with or without food

Cons

  • Can cause nausea, diarrhea, and stomach pain
  • Not approved for children

Common Side Effects for Foundayo

  • Nausea (26-35%)
  • Constipation (20-27%)
  • Diarrhea (21-25%)
  • Vomiting (13-24%)
  • Indigestion (12-16%)
  • Stomach pain (13-14%)
  • Headache (8-9%)
  • Bloating (7-9%)
  • Feeling tired (6-9%)
  • Belching (6-8%)
  • Gastroesophageal reflux disease (GERD; 6-7%)
  • Having a lot of gas (5-6%)
  • Hair loss (4-5%)

Warnings for Foundayo

  • Possible risk of thyroid cancer
  • Severe stomach side effects
  • Kidney damage
  • Inflammation of the pancreas (pancreatitis)
  • Gallbladder problems
  • Low blood sugar
  • Allergic reactions
  • Eye problems in people with Type 2 diabetes (diabetic retinopathy)
  • Lung problems during general anesthesia or deep sedation

Summary for Mounjaro

Prescription only

Mounjaro (tirzepatide) is a prescription injection used to improve blood sugar control in people 10 years and older with Type 2 diabetes. It works best when you also follow a nutritious diet and exercise regularly. Mounjaro (tirzepatide) belongs to the drug class called GIP and GLP-1 agonists. The dosage is convenient because it's injected under the skin once a week. Some common side effects of Mounjaro (tirzepatide) include nausea and diarrhea. It can also lower your appetite, which might lead to some weight loss.

Indications for Mounjaro

Pros and Cons for Mounjaro

Pros

  • Given once weekly
  • Can lower A1C by an average of up to 2.3% in about 9 months
  • Has different forms some people can choose from (vials, single-dose injectable pens, multi-dose KwikPens)
  • Can use if you have liver or kidney problems

Cons

  • Must give as an injection given under the skin
  • Can cause unpleasant side effects like nausea, vomiting, and diarrhea
  • Takes time to reach a dose that works well
  • Might not be safe during pregnancy

Common Side Effects for Mounjaro

  • Nausea (12-18%)
  • Diarrhea (12-17%)
  • Low appetite (5-11%)
  • Vomiting (5-9%)
  • Indigestion (5-8%)
  • Constipation (6-7%)
  • Stomach pain (5-6%)

Warnings for Mounjaro

  • Risk of thyroid cancer
  • Inflammation of the pancreas (pancreatitis)
  • Low blood sugar (hypoglycemia) when used with other diabetes medications
  • Allergic reactions
  • Stomach side effects
  • Kidney damage due to dehydration
  • Eye problems in people with diabetic retinopathy
  • Gallbladder problems
  • Lung problems during general anesthesia or deep sedation
  • Don't share Mounjaro KwikPens with anyone

Prices with our coupons for Foundayo vs. Mounjaro

Price Card Drug Icon
Foundayo30 tablets / 0.8mg
$149.00$780.02
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Price Card Drug Icon
Mounjaro1 carton / 4 pens of 2.5mg/0.5ml
$1,096.46$1,334.49
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