Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Budesonide (Eohilia) and dupilumab (Dupixent) are both used to treat eosinophilic esophagitis (EoE), but they belong to different medication classes. Budesonide is a corticosteroid, while dupilumab is a monoclonal antibody. Budesonide is taken orally as a suspension, typically twice a day, and is specifically FDA-approved for EoE in people aged 11 and older. Dupilumab, on the other hand, is given as a subcutaneous injection and is approved for EoE in adults and children as young as 1 year old. It's also approved for several other conditions, such as asthma, eczema, and chronic obstructive pulmonary disease (COPD). Budesonide can cause side effects like respiratory infections and fungal infections in the mouth, while dupilumab may lead to injection site reactions and eye inflammation. Budesonide interacts with medications like ritonavir and erythromycin, whereas live vaccines should be avoided with dupilumab. Neither medication is available as a generic.
Eohilia (budesonide)
Dupixent (dupilumab)
Eohilia (budesonide)
Dupixent (dupilumab)
Summary of Eohilia vs. Dupixent
Summary for Corticosteroid
Prescription only
Eohilia (budesonide) is a corticosteroid that's FDA approved to treat eosinophilic esophagitis (EoE) in adults and children. The dosage is typically a packet taken by mouth twice daily on an empty stomach. Side effects include respiratory tract infection, oral thrush, and headache. It hasn't been shown to be safe and effective for longer than 12 weeks.
Summary for Interleukin antagonist
Prescription only
Dupixent (dupilumab) is an injection that helps treat certain inflammatory conditions. This includes eczema, asthma, and chronic obstructive pulmonary disease (COPD), among others. It's a biologic medication known as an interleukin antagonist that lowers inflammation. Dupixent (dupilumab) comes as prefilled pens and prefilled syringes. It's injected under the skin of the belly or thighs (or in the back of the upper arm with someone's help). The dosing schedule depends on the condition you have, your age, and your weight. It's injected either every week, every 2 weeks, or every 4 weeks. Side effects include injection site reactions and eye problems.