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Botox Cosmetic vs. Daxxify

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Botox Cosmetic (onabotulinumtoxinA) and Daxxify (daxibotulinumtoxinA) are both neuromuscular blockers used to temporarily improve the appearance of frown lines. They work by relaxing muscles to reduce wrinkles. However, they have some differences. Botox Cosmetic is specifically approved for frown lines, forehead lines, and crow's feet, while Daxxify is approved for frown lines and neck spasms (cervical dystonia). Botox Cosmetic is typically injected every 3 months, with effects lasting up to 4 months, whereas Daxxify can last up to 6 months or longer. Both medications are only available as injections given by a healthcare provider, but neither is available in a generic form. Common side effects for both include headache, drooping eyelids, injection site reactions and muscle weakness. Both medications carry risks of serious side effects if the toxin spreads beyond the injection site, so it's important to follow your provider's instructions carefully.

Botox Cosmetic

(onabotulinumtoxinA)

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Daxxify

 

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Summary for Botox Cosmetic

Prescription only

Botox Cosmetic (onabotulinumtoxinA) is a prescription injection used in adults to temporarily improve the look of facial lines. It's FDA approved to treat moderate to severe frown lines between the eyebrows, forehead lines, crow’s feet, and neck lines. The medication is injected directly into the facial muscles by a trained healthcare professional. Side effects can vary depending on the injection site and can include headache and droopy eyelids.

Botox Cosmetic (onabotulinumtoxinA) is different from medical Botox, which is used for certain health conditions like migraines or muscle spasms.

Indications for Botox Cosmetic

Temporarily improves the appearance of moderate to severe facial lines, including:

  • Frown lines
  • Crow's feet
  • Forehead lines
  • Neck lines

Pros and Cons for Botox Cosmetic

Pros

  • Can treat many facial and neck lines at the same time
  • Might start to see results within days
  • Lasts up to 3 to 4 months
  • Quick recovery time after injections

Cons

  • Needs to be injected by a trained healthcare professional
  • Injections can be uncomfortable
  • Not permanent, requires repeat injections
  • Side effects include droopy eyelids and headache

Common Side Effects for Botox Cosmetic

Frown lines:

  • Droopy eyelids (3%)

Crow's feet:

  • Eyelid swelling (1%)

Forehead lines:

  • Headache (9%)

Warnings for Botox Cosmetic

  • Spread of toxin effect
  • Serious allergic reaction
  • Heart-related side effects
  • Difficulty swallowing or breathing
  • Eye and vision problems
  • Transmission of diseases

Summary for Daxxify

Prescription only

Daxxify (daxibotulinumtoxinA or daxibotulinumtoxinA-lanm) is an FDA-approved medication for adults to temporarily improve the appearance of frown lines (wrinkles between your eyebrows and in your forehead). It's also used to treat cervical dystonia (muscle spasms in the neck). This medication is injected into the muscles by a trained healthcare provider. Common side effects include headache and pain at the injection site. Daxxify seems to last longer than other botulinum toxin injections (e.g., Botox).

Indications for Daxxify

  • Temporary improvement in the appearance of moderate-to-severe frown lines (glabellar lines) in adults
  • Neck spasms (cervical dystonia) in adults

Pros and Cons for Daxxify

Pros

  • Works well to improve the look of frown lines
  • Can last for up to 6 months or longer for moderate-to-severe frown lines
  • Injected directly into the muscles causing your condition to help them relax
  • Given by a trained healthcare provider

Cons

  • Injections can be painful
  • Can cause headache and muscle weakness
  • Requires repeat injections since effects are temporary
  • Brand only

Common Side Effects for Daxxify

Frown lines

  • Headache (6%)
  • Injection site reactions (e.g., pain, redness, swelling; 6%)
  • Drooping eyelids (2%)
  • Trouble moving parts of the face (1%)

Cervical dystonia

  • Headache (7-9%)
  • Injection site reactions (e.g., pain, redness; up to 8%)
  • Upper respiratory tract infection (up to 5%)
  • Muscle weakness (2-5%)
  • Muscle and bone pain (4%)
  • Trouble swallowing (2-4%)
  • Spine pain (2-3%)

Warnings for Daxxify

  • Spread of toxin effects
  • Allergic reaction
  • Worsening of certain conditions
  • Difficulty swallowing or breathing
  • Reduced blinking, dry eye, and vision changes (when used for frown lines)

Prices with our coupons for Botox Cosmetic vs. Daxxify

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Botox Cosmetic1 vial / 50 units
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Daxxify1 vial / 100 units
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