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Melanocortin Receptor Agonists

Melanocortin receptor agonists are used to treat low libido. They work by activating melanocortin receptors.

Why are melanocortin receptor agonists prescribed?

  1. Low Libido (33%)
  2. Porphyria (33%)
  3. Weight Loss (33%)

Key takeaways

Melanocortin receptor agonists are used to treat low sexual drive in people who haven't gone through menopause, obesity due to specific genetic conditions, and sun sensitivity from a certain condition. These medications work by activating melanocortin receptors in your body, which can influence sexual desire, appetite, and skin pigmentation. Melanocortin receptor agonists come in different forms, including injectables and implants. Examples include bremelanotide (Vyleesi), setmelanotide (Imcivree), and afamelanotide (Scenesse). You can discuss with your prescriber to find the medication that best fits your needs.

Prices for popular Melanocortin Receptor Agonists medications
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SETMELANOTIDE promotes weight loss in people who have genetic conditions. It may also be used to maintain weight loss. It works by decreasing appetite and increasing your metabolism.
AFAMELANOTIDE treats erythropoietic protoporphyria (EPP). It works by helping your body make melanin, a pigment that helps protect your skin. This reduces your sensitivity to light, which helps prevent painful skin reactions.
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Vyleesi

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Vyleesi (bremelanotide) is used to treat hypoactive (low) sexual desire disorder (HSDD) in women who have not gone through menopause, who have not had low sexual desire in the past, and who have low sexual desire no matter the type of sexual activity, the situation, or the sexual partner. Vyleesi is a Melanocortin Receptor Agonist, which works by by activating melanocortin receptors. Vyleesi is available as a 1.75mg/0.3ml autoinjector. There are currently no generic alternatives for Vyleesi. It is covered by some Medicare and insurance plans.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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