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Compare Plenity vs. Wegovy

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Plenity
    Wegovy (semaglutide)
  • Plenity
    Wegovy (semaglutide)

  • Summary of Plenity vs. Wegovy

    Summary for Medical device
    Prescription only

    Plenity is an FDA-cleared medical device in pill form that's used for weight loss. It's taken by mouth along with a healthy diet and regular exercise through a weight management program that's supervised by a healthcare provider. Plenity is made up of natural ingredients (cellulose and citric acid). Since it works directly in your digestive tract, Plenity can help you feel full and eat less. But it might cause side effects like diarrhea, constipation, and bloating. Plenity is not a medication, and it might not be safe for people with stomach issues.

    Summary for GLP-1 agonist
    Prescription only

    Wegovy (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist that's injected under the skin. It's used together with a lower-calorie diet and regular exercise. Wegovy (semaglutide) is approved to help with weight loss in certain adults and children 12 years of age and older. It also helps lower the risk of heart attack, stroke, and death due to heart problems in adults with a larger body size and heart disease. The dosing schedule for the injections is once a week. Common side effects include nausea, diarrhea, and stomach pain.

  • Indications of Plenity vs. Wegovy

    Indications for
    •Weight loss, used in addition to a healthy diet and regular exercise
    Indications for
    •

    Weight loss and long-term weight management in:

    •People ages 12 years and older who are considered obese
    •Adults considered overweight with at least one weight-related condition (e.g., high blood pressure, Type 2 diabetes, high cholesterol)
    •

    Lowering the risk of heart attack, stroke, and death due to heart problems in adults with a larger body size and heart disease

  • Pros and Cons of Plenity vs. Wegovy

    Pros and Const for Medical device
    Pros
    •Generally few side effects
    •Is not a medication
    Cons
    •Need to take three pills for each dose
    •Might need to avoid or use with caution if you have stomach issues or trouble swallowing
    Pros and Const for GLP-1 agonist
    Pros
    •Can help you lose weight when it's used along with a nutritious diet and regular exercise
    •Approved for helping with weight loss for children ages 12 years and older considered obese
    •Injected once a week
    Cons
    •Must inject under the skin
    •Can cause stomach pain, nausea, and diarrhea
    •Can't take with other semaglutide products (Ozempic, Rybelsus) or with other GLP-1 agonists

  • Common Side Effects of Plenity vs. Wegovy

    Common Side Effects for
    •Diarrhea (13%)
    •Bloating or swelling in the stomach area (12%)
    •Common cold symptoms (12%)
    •Passing gas (9%)
    •Constipation or not having bowel movements often (5-9%)
    •Headache (7%)
    •Stomach pain (5%)
    •Nausea (5%)

    In clinical studies, there were no overall differences in the rate of side effects between those using Plenity and those using placebo.

    Common Side Effects for
    •Nausea (44%)
    •Diarrhea (30%)
    •Vomiting (24%)
    •Constipation (24%)
    •Stomach pain (20%)
    •Headache (14%)
    •Tiredness (11%)

  • Warnings of Plenity vs. Wegovy

    Common Side Effects for
    •Trouble swallowing Plenity
    •Caution in people with stomach issues
    •Not a food substitute
    Common Side Effects for
    •Possible risk for thyroid cancer
    •Inflammation of the pancreas (pancreatitis)
    •Gallbladder problems
    •Low blood sugar
    •Kidney damage
    •Allergic reactions
    •Eye problems in people with Type 2 diabetes (diabetic retinopathy)
    •Faster heart rate
    •Possible risk of self-harm
    •Lung problems during general anesthesia or deep sedation

  • Prices with our coupons for Plenity vs. Wegovy

    Learn more about Plenity
    Learn more about Wegovy

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